N S GONZALEZ
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Explore the profile of N S GONZALEZ including associated specialties, affiliations and a list of published articles.
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32
Citations
283
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Recent Articles
1.
Comings D, GONZALEZ N, Cheng Li S, Macmurray J
Am J Med Genet B Neuropsychiatr Genet
. 2003 Mar;
118B(1):110-4.
PMID: 12627476
The usual approach for using single base pair polymorphisms (SNPs) for the investigation of the genetics of behavioral disorders is to examine a single diagnostic syndrome or personality trait based...
2.
GONZALEZ N, Huber A, Algranati I
FEBS Lett
. 2001 Dec;
508(3):323-6.
PMID: 11728444
Trypanosomatid parasites containing a metabolically unstable ornithine decarboxylase (ODC) are naturally resistant to high levels of alpha-difluoromethylornithine (DFMO) because this ODC inhibitor, though causing a drastic reduction of intracellular putrescine,...
3.
Communi D, GONZALEZ N, Detheux M, Brezillon S, Lannoy V, Parmentier M, et al.
J Biol Chem
. 2001 Sep;
276(44):41479-85.
PMID: 11546776
We have cloned and expressed a novel human G-protein-coupled receptor closely related to the human P2Y(12) receptor. It corresponds to the orphan receptor called GPR86. GPR86 proved to be a...
4.
Carrillo C, CEJAS S, Cortes M, Ceriani C, Huber A, GONZALEZ N, et al.
Biochem Biophys Res Commun
. 2000 Dec;
279(2):663-8.
PMID: 11118342
alpha-Difluoromethylornithine (DFMO), the specific and irreversible inhibitor of ornithine decarboxylase (ODC), was able to induce the arrest of proliferation in Leishmania mexicana and ODC-transformed Trypanosoma cruzi cultures grown in a...
5.
Comings D, Johnson J, GONZALEZ N, Huss M, SAUCIER G, McGue M, et al.
Psychiatr Genet
. 2000 Jul;
10(1):39-42.
PMID: 10909127
The noradrenergic system has been implicated in arousal, vigilance, irritability hostility, and memory. This suggests the hypothesis that genetic variants at noradrenergic receptors may be risk factors of these behaviors....
6.
Carrillo C, CEJAS S, GONZALEZ N, Algranati I
FEBS Lett
. 1999 Aug;
454(3):192-6.
PMID: 10431805
Trypanosoma cruzi, a pathogenic protozoan causing Chagas disease, lacks ornithine decarboxylase (ODC), the enzyme catalyzing the first step of polyamine biosynthetic pathway in eukaryotic cells. Our results indicate that the...
7.
Sanchez C, Mucci J, GONZALEZ N, Ochoa A, Zakin M, Algranati I
Biochem J
. 1997 Jun;
324 ( Pt 3):847-53.
PMID: 9210409
Proliferation of Leishmania mexicana promastigotes in synthetic medium can be blocked by the depletion of intracellular polyamine pools induced by the presence of D,L-alpha-difluoromethylornithine (DFMO), a specific and irreversible inhibitor...
8.
Sanchez C, Sidrauski C, Freire S, GONZALEZ N, Algranati I
Biochem Biophys Res Commun
. 1995 Jul;
212(2):396-403.
PMID: 7626053
The catalytic properties of ornithine decarboxylase (ODC) from Leishmania mexicana as well as the interaction with its cofactor pyridoxal 5'-phosphate (PLP) and the irreversible inhibitor alpha-difluoromethylornithine (DFMO) have been studied...
9.
GONZALEZ N, Algranati I
Cell Mol Biol (Noisy-le-grand)
. 1994 Nov;
40(7):907-14.
PMID: 7849558
Putrescine uptake of Leishmania mexicana promastigotes is tightly regulated by polyamine intracellular concentrations. This uptake, markedly stimulated after parasite treatment with alpha-difluoromethylornithine (DFMO) for 48 to 72 hrs., was strongly...
10.
GONZALEZ N, Ceriani C, Algranati I
Biochem Biophys Res Commun
. 1992 Oct;
188(1):120-8.
PMID: 1417835
Putrescine uptake in Trypanosoma cruzi epimastigotes is 10 to 50-fold higher than in Leishmania mexicana or Crithidia fasciculata. Polyamine transport in all these trypanosomatids is an energy-dependent process strongly inhibited...