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N R Hunter

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Articles 58
Citations 603
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11.
Milross C, Mason K, Hunter N, Terry N, Patel N, Harada S, et al.
Eur J Cancer . 1997 Jul; 33(8):1299-308. PMID: 9301459
Paclitaxel is a potent chemotherapeutic drug and also has the potential to act as a radioenhancing agent. The latter is based on its ability to arrest cells in the radiosensitive...
12.
Li C, Yu D, Inoue T, Yang D, Tansey W, Liu C, et al.
J Nucl Med . 1997 Jul; 38(7):1042-7. PMID: 9225788
Unlabelled: Paclitaxel, an antineoplastic agent that stabilizes microtubules and arrests cells in the G2/M cell cycle phase, has shown activity against many common cancers, including ovarian and breast tumors. In...
13.
Seong J, Milross C, Hunter N, Shin H, Milas L
Anticancer Drugs . 1997 Jan; 8(1):80-7. PMID: 9147616
We studied the combination of tumor necrosis factor (TNF) and paclitaxel. Our aim was to determine whether TNF increases the antitumor efficacy of paclitaxel and if so whether the increase...
14.
Milross C, Tucker S, Mason K, Hunter N, Peters L, Milas L
Acta Oncol . 1997 Jan; 36(2):183-9. PMID: 9140436
Tumor necrosis and oxygen status were investigated as a function of tumor size in three syngeneic murine carcinomas, MCa-4, OCa-I, and SCC-VII, in C3Hf/Kam mice. Tumor necrosis was estimated histologically,...
15.
Gregoire V, Hunter N, Brock W, Hittelman W, Plunkett W, Milas L
Radiat Res . 1996 Nov; 146(5):548-53. PMID: 8896581
Fludarabine, an effective repair inhibitor of radiation-induced chromosome breaks, and indomethacin, an inhibitor of prostaglandin synthesis, were shown previously to improve the therapeutic ratio of radiotherapy for murine tumors. The...
16.
Milross C, Mason K, Hunter N, Chung W, Peters L, Milas L
J Natl Cancer Inst . 1996 Sep; 88(18):1308-14. PMID: 8797771
Background: Microtubules are cellular organelles with functions that include control of cell division by mitosis, cell morphology, and transport of material within the cell. The anticancer drug paclitaxel (Taxol) promotes...
17.
Li C, Yu D, Inoue T, Yang D, Milas L, Hunter N, et al.
Anticancer Drugs . 1996 Aug; 7(6):642-8. PMID: 8913432
Water-soluble paclitaxel may cause less side effects and be less costly to administer in comparison to a taxol formulation using a cremophor EL/alcohol vehicle. In this study, polyethylene glycol (PEG;...
18.
Milross C, Peters L, Hunter N, Mason K, Milas L
Int J Cancer . 1995 Sep; 62(5):599-604. PMID: 7665232
The established antitumor efficacy of paclitaxel and cisplatin as single agents and their distinctly different mechanisms of action have prompted laboratory and clinical research into their use in combination. Our...
19.
Milas L, Hunter N, Mason K, Milross C, Saito Y, Peters L
Cancer Res . 1995 Aug; 55(16):3564-8. PMID: 7627965
We reported previously (L. Milas et al., Cancer Res., 54: 3506-3510, 1994) that paclitaxel greatly enhances the response of a murine mammary carcinoma to subsequent irradiation and hypothesized that the...
20.
Meyn R, Stephens L, Hunter N, Milas L
Anticancer Drugs . 1995 Jun; 6(3):443-50. PMID: 7670143
There is increasing attention directed to the hypothesis that apoptosis plays a role in the response to cancer treatment including chemotherapy. However, the evidence to support this hypothesis has come...