N N Iscove
Overview
Explore the profile of N N Iscove including associated specialties, affiliations and a list of published articles.
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Articles
63
Citations
1506
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Recent Articles
1.
Ichim C, Atkins H, Iscove N, Wells R
Leukemia
. 2011 Jun;
25(11):1687-96.
PMID: 21637284
Identification of genes that regulate clonogenicity of acute myelogenous leukemia (AML) cells is hindered by the difficulty of isolating pure populations of cells with defined proliferative abilities. By analyzing the...
2.
Khoury H, Barbara M, Iscove N, Minden M
Leukemia
. 2011 Jan;
25(4):711-3.
PMID: 21233835
No abstract available.
3.
Faubert A, Chagraoui J, Mayotte N, Frechette M, Iscove N, Humphries R, et al.
Cold Spring Harb Symp Quant Biol
. 2008 Nov;
73:555-64.
PMID: 19022763
Determinants regulating short- and long-term repopulating hematopoietic stem cell (STR-HSC and LTR-HSC) self-renewal remain largely uncharacterized. To gain further insights into HSC self-renewal, we investigated possible genetic interactions between two...
4.
Billia F, Barbara M, McEwen J, Trevisan M, Iscove N
Blood
. 2001 Apr;
97(8):2257-68.
PMID: 11290586
Although hematopoiesis is known to proceed from stem cells through a graded series of multipotent, oligopotent, and unipotent precursor cells, it has been difficult to resolve these cells physically one...
5.
Fernandes M, Iscove N, Gingras G, Calabretta B
Genomics
. 2000 Oct;
69(2):263-70.
PMID: 11031109
We report the identification and characterization of a novel C-type lectin gene, named HECL (HGMW-approved symbol CLECSF7), that maps close to the natural killer gene complex on human chromosome 12p13....
6.
Boehmelt G, Wakeham A, Elia A, Sasaki T, Plyte S, Potter J, et al.
EMBO J
. 2000 Oct;
19(19):5092-104.
PMID: 11013212
The hexosamine pathway provides UDP-N:-acetylhexosamine donor substrates used in cytosolic and Golgi-mediated glycosylation of proteins and for formation of glycosylphosphatidylinositol (GPI) anchors, which tether proteins to the outer plasma membrane....
7.
Singh N, Phillips R, Iscove N, Egan S
Exp Hematol
. 2000 May;
28(5):527-34.
PMID: 10812242
Objective: Hematopoiesis is the process by which mature blood cell types are generated from a small population of pluripotent hematopoietic stem cells. How these cells undergo fate selection, however, is...
8.
Boehmelt G, Fialka I, Brothers G, McGinley M, Patterson S, Mo R, et al.
J Biol Chem
. 2000 Apr;
275(17):12821-32.
PMID: 10777580
N-Linked glycosylation is a post-translational modification occurring in many eukaryotic secreted and surface-bound proteins and has impact on diverse physiological and pathological processes. Similarly important is the generation of glycosylphosphatidylinositol...
9.
Brail L, Jang A, Billia F, Iscove N, Klamut H, Hill R
Mutat Res
. 1999 Sep;
406(2-4):45-54.
PMID: 10479721
The determination of the gene expression pattern of single cells has important implications for many areas of cellular and developmental biology including lineage determination, identification of primitive stem cells and...
10.
Fernandes M, Finnegan A, Siracusa L, Brenner C, Iscove N, Calabretta B
Cancer Res
. 1999 Jun;
59(11):2709-17.
PMID: 10363996
A novel type II integral membrane protein has been identified in the course of screening for genes overexpressed in a mouse model of chronic myelogenous leukemia blast crisis. This new...