N Methia
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Explore the profile of N Methia including associated specialties, affiliations and a list of published articles.
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10
Citations
475
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Recent Articles
1.
Methia N, Andre P, Hafezi-Moghadam A, Economopoulos M, Thomas K, Wagner D
Mol Med
. 2002 Feb;
7(12):810-5.
PMID: 11844869
Background: Apolipoprotein E (apoE) mediates lipoprotein uptake by receptors such as the LDL receptor (LDLR). The isoform apoE4 has been linked to Alzheimer's disease and to poor outcomes after brain...
2.
Methia N, Andre P, Denis C, Economopoulos M, Wagner D
Blood
. 2001 Aug;
98(5):1424-8.
PMID: 11520791
To examine the role of the platelet adhesion molecule von Willebrand factor (vWf) in atherogenesis, vWf-deficient mice (vWf-/-) were bred with mice lacking the low-density lipoprotein receptor (LDLR-/-) on a...
3.
Methia N, Denis C, Wagner D
Eur J Cell Biol
. 2000 Feb;
78(12):884-91.
PMID: 10669107
Sorting of von Willebrand factor precursor (pro-vWf) from the trans-Golgi network to secretory granules (Weibel-Palade bodies) is critical for its conversion to the biologically active highly multimeric form, as well...
4.
Denis C, Methia N, Frenette P, Rayburn H, Hynes R, Wagner D
Proc Natl Acad Sci U S A
. 1998 Aug;
95(16):9524-9.
PMID: 9689113
von Willebrand factor (vWf) deficiency causes severe von Willebrand disease in humans. We generated a mouse model for this disease by using gene targeting. vWf-deficient mice appeared normal at birth;...
5.
Vainchenker W, Methia N, Debili N, Titeux M, Wendling F
Thromb Haemost
. 1995 Jul;
74(1):526-8.
PMID: 8578519
v-mpl is a mouse oncogene that is part of the genome of the myeloproliferative leukemia virus (MPLV). The cellular homolog gene c-mpl encodes an hematopoietic cytokine receptor mainly restricted to...
6.
Methia N, Debili N, Titeux M, Vainchenker W, Wendling F
C R Acad Sci III
. 1995 Apr;
318(4):479-82.
PMID: 7648360
v-mpl is a mouse oncogene that is part of the genome of the myeloproliferative leukemia virus (MPLV). The cellular homolog gene c-mpl encodes an hematopoietic cytokine receptor restricted to the...
7.
Debili N, Wendling F, Cosman D, Titeux M, Florindo C, Dusanter-Fourt I, et al.
Blood
. 1995 Jan;
85(2):391-401.
PMID: 7529061
The Mpl receptor (Mpl-R) is a cytokine receptor belonging to the hematopoietin receptor superfamily for which a ligand has been recently characterized. To study the lineage distribution of Mpl-R in...
8.
Wendling F, Maraskovsky E, Debili N, Florindo C, Teepe M, Titeux M, et al.
Nature
. 1994 Jun;
369(6481):571-4.
PMID: 8202160
Megakaryocytopoiesis is the cellular developmental process that leads to platelet production. At least two humoral growth factors may be necessary for megakaryocyte proliferation and maturation. One is a megakaryocyte-colony stimulating...
9.
Vainchenker W, Debili N, Methia N, Mouthon M, Wendling F
Bull Acad Natl Med
. 1994 May;
178(5):753-78; discussion 778-9.
PMID: 7953887
Hematopoiesis is the cellular system which leads to the continuous production of blood cells. This highly complex cellular system is organized into three main compartments: (i) stem cells which are...
10.
Methia N, Louache F, Vainchenker W, Wendling F
Blood
. 1993 Sep;
82(5):1395-401.
PMID: 7689867
The proto-oncogene c-mpl encodes a protein whose sequence shares striking homologies with members of the highly conserved hematopoietin receptor superfamily. This gene had been transduced in a truncated form by...