N Debili
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Explore the profile of N Debili including associated specialties, affiliations and a list of published articles.
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81
Citations
1365
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Recent Articles
1.
Palazzo A, Bluteau O, Messaoudi K, Marangoni F, Chang Y, Souquere S, et al.
J Thromb Haemost
. 2016 Sep;
14(12):2524-2535.
PMID: 27685868
Summary: Background Cytoskeletal rearrangements are essential for platelet release. The RHO small GTPase family, as regulators of the actin cytoskeleton, play an important role in proplatelet formation (PPF). In the...
2.
Chen Y, Boukour S, Milloud R, Favier R, Saposnik B, Schlegel N, et al.
J Thromb Haemost
. 2013 Oct;
11(12):2163-75.
PMID: 24165359
Background: Mutations in the MYH9 gene cause autosomal dominant MYH9-related diseases (MYH9-RD) that associate macrothrombocytopenia with various other clinical conditions. The mechanisms giving rise to giant platelets remain poorly understood....
3.
Ali A, Bluteau O, Messaoudi K, Palazzo A, Boukour S, Lordier L, et al.
Cell Death Dis
. 2013 Jul;
4:e738.
PMID: 23887629
Abexinostat is a pan histone deacetylase inhibitor (HDACi) that demonstrates efficacy in malignancy treatment. Like other HDACi, this drug induces a profound thrombocytopenia whose mechanism is only partially understood. We...
4.
Bluteau O, Langlois T, Rivera-Munoz P, Favale F, Rameau P, Meurice G, et al.
J Thromb Haemost
. 2013 Jun;
11(9):1730-41.
PMID: 23782903
Background: The molecular bases of the cellular changes that occur during human megakaryocyte (MK) ontogeny remain unknown, and may be important for understanding the significance of MK differentiation from human...
5.
Nakatake M, Monte-Mor B, Debili N, Casadevall N, Ribrag V, Solary E, et al.
Oncogene
. 2011 Jul;
31(10):1323-33.
PMID: 21785463
JAK2(V617F) is a gain of function mutation that promotes cytokine-independent growth of myeloid cells and accounts for a majority of myeloproliferative neoplasms (MPN). Mutations in p53 are rarely found in...
6.
Gabet A, Coulon S, Fricot A, Vandekerckhove J, Chang Y, Ribeil J, et al.
Cell Death Differ
. 2010 Nov;
18(4):678-89.
PMID: 21072057
Stem cell factor (SCF) and erythropoietin are strictly required for preventing apoptosis and stimulating proliferation, allowing the differentiation of erythroid precursors from colony-forming unit-E to the polychromatophilic stage. In contrast,...
7.
Ragu C, Boukour S, Elain G, Wagner-Ballon O, Raslova H, Debili N, et al.
Leukemia
. 2010 Apr;
24(6):1227-30.
PMID: 20428204
No abstract available.
8.
Bluteau D, Lordier L, Di Stefano A, Chang Y, Raslova H, Debili N, et al.
J Thromb Haemost
. 2009 Jul;
7 Suppl 1:227-34.
PMID: 19630806
Each day in every human, approximately 1 x 10(11) platelets are produced by the cytoplasmic fragmentation of megakaryocytes (MK), their marrow precursor cells. Platelets are the predominating factor in the...
9.
Schaffner-Reckinger E, Salsmann A, Debili N, Bellis J, de Mey J, Vainchenker W, et al.
J Thromb Haemost
. 2009 Jun;
7(7):1207-17.
PMID: 19486276
Background: We have recently reported a novel mutation in the beta3 subunit of the platelet fibrinogen receptor (alpha(IIb)beta3D723H) identified in a patient with dominantly inherited macrothrombocytopenia, and we have shown...
10.
Chang Y, Bluteau D, Debili N, Vainchenker W
J Thromb Haemost
. 2007 Aug;
5 Suppl 1:318-27.
PMID: 17635743
Megakaryocytopoiesis is the process that leads to the production of platelets. This process involves the commitment of multipotent hematopoietic stem cells toward megakaryocyte (MK) progenitors, the proliferation and differentiation of...