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N L Harvey

Explore the profile of N L Harvey including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 265
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11.
Colussi P, Harvey N, Kumar S
J Biol Chem . 1998 Sep; 273(38):24535-42. PMID: 9733748
Caspases are cysteine proteases that play an essential role in apoptosis by cleaving several key cellular proteins. Despite their function in apoptosis, little is known about where in the cell...
12.
Harvey K, Harvey N, Michael J, Parasivam G, Waterhouse N, Alnemri E, et al.
J Biol Chem . 1998 Jun; 273(22):13524-30. PMID: 9593687
The onset of apoptosis is coupled to the proteolytic activation of a family of cysteine proteases, termed caspases. These proteases cleave their target proteins after an aspartate residue. Following caspase...
13.
BUTT A, Harvey N, Parasivam G, Kumar S
J Biol Chem . 1998 Apr; 273(12):6763-8. PMID: 9506977
Nedd2 (caspase-2) is a cysteine protease of the caspase family that has been demonstrated to play a role in the apoptotic pathway. The 51-kDa precursor of Nedd2 undergoes cleavage into...
14.
Harvey N, BUTT A, Kumar S
J Biol Chem . 1997 May; 272(20):13134-9. PMID: 9148927
The ICE/CED-3 family of proteases (caspases) play a central role in the execution phase of apoptosis. These proteases are synthesised as precursor molecules that require processing at specific aspartate residues...
15.
Harvey N, Trapani J, Fernandes-Alnemri T, Litwack G, Alnemri E, Kumar S
Genes Cells . 1996 Jul; 1(7):673-85. PMID: 9078393
Background: The Nedd2/Ich-1 protein belongs to a growing family of mammalian cysteine proteases similar to interleukin-1 beta converting enzyme (ICE). Because of their similarity to the Cacnorhabditis elegans cell death...
16.
Cole S, Aylett G, Harvey N, Cambareri A, Ashman L
Leukemia . 1996 Feb; 10(2):288-96. PMID: 8637238
Cell surface levels of the receptor tyrosine kinase P145(c-kit), the product of the c-kit proto-oncogens, in a panel of 80 primary adult acute myeloid leukaemia (AML) specimens collected at presentation...
17.
Kumar S, Harvey N
FEBS Lett . 1995 Nov; 375(3):169-73. PMID: 7498492
A family of mammalian homologues of the Caenorhabditis elegans cell death protein Ced-3 has been recently discovered. These mammalian proteins encode novel cysteine proteases with homology to the interleukin-1 beta...
18.
Harvey N, Fewson C, HOLMS W
Lab Pract . 1968 Oct; 17(10):1134-6. PMID: 4879312
No abstract available.