N L Craig
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Explore the profile of N L Craig including associated specialties, affiliations and a list of published articles.
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57
Citations
2467
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Recent Articles
1.
Peters J, Craig N
Nat Rev Mol Cell Biol
. 2001 Nov;
2(11):806-14.
PMID: 11715047
A notable feature of transposable elements--segments of DNA that can move from one position to another in genomes--is that they are highly prevalent, despite the fact that their translocation can...
2.
Rao J, Craig N
J Mol Biol
. 2001 Apr;
307(5):1161-70.
PMID: 11292332
The bacterial transposon Tn7 is distinguished among mobile genetic elements by its targeting abilities. Recently, we reported that Tn7 is able to selectively insert adjacent to triple-helical DNA. The binding...
3.
Peters J, Craig N
Genes Dev
. 2001 Mar;
15(6):737-47.
PMID: 11274058
We report that the bacterial transposon Tn7 selects targets by recognizing features associated with DNA replication using the transposon-encoded DNA-binding protein TnsE. We show that Tn7 transposition directed by TnsE...
4.
Kuduvalli P, Rao J, Craig N
EMBO J
. 2001 Feb;
20(4):924-32.
PMID: 11179236
The bacterial transposon Tn7 utilizes four Tn7-encoded proteins, TnsA, TnsB, TnsC and TnsD, to make insertions at a specific site termed attTn7. This target is selected by the binding of...
5.
Stellwagen A, Craig N
J Mol Biol
. 2001 Jan;
305(3):633-42.
PMID: 11152618
The bacterial transposon Tn7 is distinguished by its unusual discrimination among targets, being particularly attracted to certain target DNA and actively avoiding other DNA. Tn7 transposition is mediated by the...
6.
Peters J, Craig N
Mol Cell
. 2000 Oct;
6(3):573-82.
PMID: 11030337
We report that the bacterial transposon Tn7 can preferentially transpose into regions where chromosomal DNA replication terminates. DNA double-strand breaks are associated with the termination of chromosomal replication; therefore, we...
7.
Hickman A, Li Y, Mathew S, May E, Craig N, Dyda F
Mol Cell
. 2000 Jul;
5(6):1025-34.
PMID: 10911996
Transposition requires a coordinated series of DNA breakage and joining reactions. The Tn7 transposase contains two proteins: TnsA, which carries out DNA breakage at the 5' ends of the transposon,...
8.
Lu F, Craig N
EMBO J
. 2000 Jul;
19(13):3446-57.
PMID: 10880457
Tn7 transposition has been hypothesized to require a heteromeric transposase formed by two Tn7-encoded proteins, TnsA and TnsB, and accessory proteins that activate the transposase when they are associated with...
9.
Deboy R, Craig N
J Bacteriol
. 2000 May;
182(11):3310-3.
PMID: 10809719
The bacterial transposon Tn7 inserts at high frequency into a specific site called attTn7, which is present in the chromosomes of many bacteria. We show here that transcription of a...
10.
Rao J, Miller P, Craig N
Proc Natl Acad Sci U S A
. 2000 Mar;
97(8):3936-41.
PMID: 10737770
We have found that the bacterial transposon Tn7 can recognize and preferentially insert adjacent to triple-helical nucleic acid structures. Both synthetic intermolecular triplexes, formed through the pairing of a short...