N E Fusenig
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Explore the profile of N E Fusenig including associated specialties, affiliations and a list of published articles.
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134
Citations
3942
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Recent Articles
1.
Fusenig N, Boukamp P, Breitkreutz D, Hulsen A, Petrusevska S, Cerutti P, et al.
Toxicol In Vitro
. 2010 Aug;
4(4-5):627-34.
PMID: 20702246
Immortalized human skin epithelial cell lines provide useful models to study progressive stages in human carcinogenesis. Alterations have been examined occurring with immortalization and malignant progression of the human keratinocyte...
2.
Smola H, Thiekotter G, Baur M, Stark H, Breitkreutz D, Fusenig N
Toxicol In Vitro
. 2010 Aug;
8(4):641-50.
PMID: 20692978
Epidermal-dermal cell-cell interactions are recognized to influence keratinocyte proliferation in vivo as well as in vitro. To study the underlying molecular mechanisms of epithelial-mesenchymal interactions epidermal-dermal cell co-cultures and organotypic...
3.
Strieth S, Hartschuh W, Pilz L, Fusenig N
Br J Cancer
. 2002 Nov;
87(11):1301-7.
PMID: 12439721
Differential diagnosis between keratoacanthomas and well differentiated squamous cell carcinomas based on clinical and histomorphological data is problematic. Recent findings of cellular atypia in a large proportion of keratoacanthomas indicated...
4.
Kiessling F, Fink C, Hansen M, Bock M, Sinn H, Schrenk H, et al.
Invest Radiol
. 2002 Mar;
37(4):193-8.
PMID: 11923641
Rationale: Malignant tumors often show an increased uptake and metabolism of plasma proteins, especially albumin. Objectives: Determine whether the accumulation of low loaded Gd-albumin improves visualization of malignant tumors by...
5.
Mueller M, Peter W, Mappes M, Huelsen A, STEINBAUER H, Boukamp P, et al.
Am J Pathol
. 2001 Oct;
159(4):1567-79.
PMID: 11583982
Tumor microenvironment is crucial for cancer growth and progression as evidenced by reports on the significance of tumor angiogenesis and stromal cells. Using the HaCaT/HaCaT-ras human skin carcinogenesis model, we...
6.
Szabowski A, Stark H, Andrecht S, Kolbus A, Schorpp-Kistner M, Angel P, et al.
J Invest Dermatol
. 2001 May;
116(5):816-20.
PMID: 11348477
Organotypic cocultures of keratinocytes and fibroblasts generate a normal epidermis irrespective of the species and tissue origin of fibroblasts. The use of mouse fibroblasts and human keratinocytes facilitates the identification...
7.
Sandalon Z, Fusenig N, McCutcheon J, Taichman L, Garlick J
Gene Ther
. 2001 Apr;
8(3):232-8.
PMID: 11313795
The potential of gene therapy to treat premalignant disease or recurrent cancer has not been investigated. The goal of the present investigation was to explore the efficacy of pro-drug-mediated, suicide...
8.
Bajou K, Masson V, Gerard R, Schmitt P, Albert V, Praus M, et al.
J Cell Biol
. 2001 Mar;
152(4):777-84.
PMID: 11266468
The plasminogen (Plg)/plasminogen activator (PA) system plays a key role in cancer progression, presumably via mediating extracellular matrix degradation and tumor cell migration. Consequently, urokinase-type PA (uPA)/plasmin antagonists are currently...
9.
Airola K, Fusenig N
J Invest Dermatol
. 2001 Feb;
116(1):85-92.
PMID: 11168802
There is accumulating evidence of the critical role of tumor stroma in carcinoma development and progression. We have studied the significance of stromal components in regulating matrix metalloproteinases in different...
10.
c-Jun and JunB antagonistically control cytokine-regulated mesenchymal-epidermal interaction in skin
Szabowski A, Andrecht S, Kolbus A, Schorpp-Kistner M, Fusenig N, Angel P
Cell
. 2000 Dec;
103(5):745-55.
PMID: 11114331
Interactions between mesenchymal and epithelial cells are responsible for organogenesis and tissue homeostasis. This mutual cross-talk involves cell surface proteins and soluble factors, which are mostly the result of regulated...