D Breitkreutz
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Explore the profile of D Breitkreutz including associated specialties, affiliations and a list of published articles.
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52
Citations
1991
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Recent Articles
1.
Fusenig N, Boukamp P, Breitkreutz D, Hulsen A, Petrusevska S, Cerutti P, et al.
Toxicol In Vitro
. 2010 Aug;
4(4-5):627-34.
PMID: 20702246
Immortalized human skin epithelial cell lines provide useful models to study progressive stages in human carcinogenesis. Alterations have been examined occurring with immortalization and malignant progression of the human keratinocyte...
2.
Smola H, Thiekotter G, Baur M, Stark H, Breitkreutz D, Fusenig N
Toxicol In Vitro
. 2010 Aug;
8(4):641-50.
PMID: 20692978
Epidermal-dermal cell-cell interactions are recognized to influence keratinocyte proliferation in vivo as well as in vitro. To study the underlying molecular mechanisms of epithelial-mesenchymal interactions epidermal-dermal cell co-cultures and organotypic...
3.
Breitkreutz D, Braiman-Wiksman L, Daum N, Denning M, Tennenbaum T
J Cancer Res Clin Oncol
. 2007 Jul;
133(11):793-808.
PMID: 17661083
The protein kinase C (PKC) family represents a large group of phospholipid dependent enzymes catalyzing the covalent transfer of phosphate from ATP to serine and threonine residues of proteins. Phosphorylation...
4.
Baumann P, Zigrino P, Mauch C, Breitkreutz D, Nischt R
Br J Cancer
. 2000 Oct;
83(10):1387-93.
PMID: 11044366
Elevated expression of type IV collagenases (MMP-2 and MMP-9) has been strongly correlated with tumour progression and metastasis in various tumours. Here, we analysed expression and activation of these MMPs...
5.
Tomakidi P, Schuster G, Breitkreutz D, Kohl A, Ottl P, Komposch G
Biomaterials
. 2000 Jul;
21(15):1549-59.
PMID: 10885727
This article explores whether organotypic cultures of immortalized gingival keratinocytes constitute a suitable model for assessing the epithelial cell compatibility of two groups of dental resins, each of them representing...
6.
Tomakidi P, Mirancea N, Fusenig N, Herold-Mende C, Bosch F, Breitkreutz D
Differentiation
. 1999 Jun;
64(5):263-75.
PMID: 10374263
Benign and malignant HaCaT-ras clones, derived from immortalized HaCaT cells were grown as nude mouse surface transplants rendering a human tumor progression model. Searching for malignancy-related alterations, the deposition, localization...
7.
Stark H, Baur M, Breitkreutz D, Mirancea N, Fusenig N
J Invest Dermatol
. 1999 May;
112(5):681-91.
PMID: 10233757
Skin equivalents formed by keratinocytes cocultured with fibroblasts embedded in collagen lattices represent promising tools for mechanistic studies of skin physiology, for pharmacotoxicologic testing, and for the use as skin...
8.
Tomakidi P, Breitkreutz D, Kohl A, Komposch G
Ann Anat
. 1999 Mar;
181(1):127-32.
PMID: 10081576
In stratified epithelia, integrins play a fundamental role in mediating basal cell attachment to a variety of extracellular matrix molecules. To assess whether keratinocyte-specific integrins are expressed in a similar...
9.
Tomakidi P, Breitkreutz D, Fusenig N, Zoller J, Kohl A, Komposch G
Cell Tissue Res
. 1998 Jun;
292(2):355-66.
PMID: 9560478
Cell-matrix interactions and the ordered deposition of basement membrane (BM) components are of major importance for the maintenance of tissue homeostasis in complex epithelia. This aspect was studied in vitro...
10.
Breitkreutz D, Schoop V, Mirancea N, Baur M, Stark H, Fusenig N
Eur J Cell Biol
. 1998 May;
75(3):273-86.
PMID: 9587059
The immortal human keratinocyte line HaCaT has been employed in many studies as paradigm for epidermal keratinocytes. In order to demonstrate its potential to form stable epidermal structures in response...