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N Cervoni

Explore the profile of N Cervoni including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 398
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Recent Articles
1.
Cervoni N, Szyf M
J Biol Chem . 2001 Aug; 276(44):40778-87. PMID: 11524416
Mammalian genomes are compartmentalized into dense inactive chromatin that is hypermethylated and active open chromatin that is hypomethylated. It is generally accepted that this bimodal pattern of methylation is established...
2.
Slack A, Cervoni N, Pinard M, Szyf M
Eur J Biochem . 1999 Aug; 264(1):191-9. PMID: 10447688
This paper tests the hypothesis that expression of the DNA methyltransferase, dnmt1, gene is regulated by a methylation-sensitive DNA element. Methylation of DNA is an attractive system for feedback regulation...
3.
Ramchandani S, Bhattacharya S, Cervoni N, Szyf M
Proc Natl Acad Sci U S A . 1999 May; 96(11):6107-12. PMID: 10339549
The pattern of DNA methylation plays an important role in regulating different genome functions. To test the hypothesis that DNA methylation is a reversible biochemical process, we purified a DNA...
4.
Slack A, Cervoni N, Pinard M, Szyf M
J Biol Chem . 1999 Apr; 274(15):10105-12. PMID: 10187792
This paper tests the hypothesis that DNA methyltransferase plays a causal role in cellular transformation induced by SV40 T antigen. We show that T antigen expression results in elevation of...
5.
Cervoni N, Bhattacharya S, Szyf M
J Biol Chem . 1999 Mar; 274(13):8363-6. PMID: 10085064
DNA methylation patterns are generated during development by a sequence of methylation and demethylation events. We have recently demonstrated that mammals bear a bona fide demethylase enzyme that removes methyl...
6.
Bhattacharya S, Ramchandani S, Cervoni N, Szyf M
Nature . 1999 Mar; 397(6720):579-83. PMID: 10050851
DNA-methylation patterns are important for regulating genome functions, and are determined by the enzymatic processes of methylation and demethylation. The demethylating enzyme has now been identified: a mammalian complementary DNA...