N C Ha
Overview
Explore the profile of N C Ha including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
698
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Recent Articles
1.
Ha N, Choi G, Choi K, Oh B
Curr Opin Struct Biol
. 2001 Dec;
11(6):674-8.
PMID: 11751047
The three-dimensional structures of Delta5-3-ketosteroid isomerases from two different bacterial species have been determined. The structures reveal an unusually apolar active site, in which each of several competitive inhibitors of...
2.
Oh B, Chang B, Park K, Ha N, Kim H, Oh B, et al.
Biochemistry
. 2001 Oct;
40(32):9669-76.
PMID: 11583167
The thermostable phytase from Bacillus amyloliquefaciens DS11 hydrolyzes phytate (myo-inositol hexakisphosphate, IP6) to less phosphorylated myo-inositol phosphates in the presence of Ca2+. In this report, we discuss the unique Ca2+-dependent...
3.
Shin S, Ha N, Oh B, Oh T, Oh B
Structure
. 2001 Sep;
9(9):851-8.
PMID: 11566134
Background: Phytases hydrolyze phytic acid (myo-inositol-hexakisphosphate) to less-phosphorylated myo-inositol derivatives and inorganic phosphate. Phytases are used in animal feed to reduce phosphate pollution in the environment. Recently, a thermostable, calcium-dependent...
4.
Choi G, Ha N, Kim M, Hong B, Oh B, Choi K
Biochemistry
. 2001 Jun;
40(23):6828-35.
PMID: 11389596
Delta5-3-ketosteroid isomerase (KSI) from Pseudomonas putida Biotype B catalyzes the allylic isomerization of Delta5-3-ketosteroids to their conjugated Delta4-isomers via a dienolate intermediate. Two electrophilic catalysts, Tyr-14 and Asp-99, are involved...
5.
Ha N, Oh S, Sung J, Cha K, Lee M, Oh B
Nat Struct Biol
. 2001 May;
8(6):505-9.
PMID: 11373617
Helicobacter pylori, an etiologic agent in a variety of gastroduodenal diseases, produces a large amount of urease, which is believed to neutralize gastric acid by producing ammonia for the survival...
6.
Shin S, Sung B, Cho Y, Kim H, Ha N, Hwang J, et al.
Biochemistry
. 2001 Feb;
40(4):1117-23.
PMID: 11170436
Survivin, an apoptosis inhibitor/cell-cycle regulator, is critically required for suppression of apoptosis and ensuring normal cell division in the G2/M phase of the cell cycle. It is highly expressed in...
7.
Oh K, Cha S, Kim D, Cho H, Ha N, Choi G, et al.
Biochemistry
. 2000 Nov;
39(45):13891-6.
PMID: 11076530
Ketosteroid isomerase (KSI) is one of the most proficient enzymes catalyzing an allylic isomerization reaction at a diffusion-controlled rate. In this study of KSI, we have detailed the structures of...
8.
Ha N, Kim M, Lee W, Choi K, Oh B
J Biol Chem
. 2000 Sep;
275(52):41100-6.
PMID: 11007792
Delta(5)-3-Ketosteroid isomerase catalyzes cleavage and formation of a C-H bond at a diffusion-controlled limit. By determining the crystal structures of the enzyme in complex with each of three different inhibitors...
9.
Kim D, Jang D, Nam G, Choi G, Kim J, Ha N, et al.
Biochemistry
. 2000 Apr;
39(16):4581-9.
PMID: 10769113
Delta(5)-3-Ketosteroid isomerase from Pseudomonas putida biotype B is one of the most proficient enzymes catalyzing an allylic isomerization reaction at rates comparable to the diffusion limit. The hydrogen-bond network (Asp99......
10.
Ha N, Oh B, Shin S, Kim H, Oh T, Kim Y, et al.
Nat Struct Biol
. 2000 Feb;
7(2):147-53.
PMID: 10655618
Phytases hydrolyze phytic acid to less phosphorylated myo-inositol derivatives and inorganic phosphate. A thermostable phytase is of great value in applications for improving phosphate and metal ion availability in animal...