N C Danbolt
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Explore the profile of N C Danbolt including associated specialties, affiliations and a list of published articles.
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62
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Recent Articles
1.
Danbolt N, Furness D, Zhou Y
Neurochem Int
. 2016 May;
98:29-45.
PMID: 27235987
Neither normal brain function nor the pathological processes involved in neurological diseases can be adequately understood without knowledge of the release, uptake and metabolism of glutamate. The reason for this...
2.
Zhou Y, Danbolt N
J Neural Transm (Vienna)
. 2014 Mar;
121(8):799-817.
PMID: 24578174
Glutamate is the most abundant free amino acid in the brain and is at the crossroad between multiple metabolic pathways. Considering this, it was a surprise to discover that glutamate...
3.
Zhou Y, Holmseth S, Hua R, Lehre A, Olofsson A, Poblete-Naredo I, et al.
Am J Physiol Renal Physiol
. 2011 Nov;
302(3):F316-28.
PMID: 22071246
The Na(+)- and Cl(-)-dependent GABA-betaine transporter (BGT1) has received attention mostly as a protector against osmolarity changes in the kidney and as a potential controller of the neurotransmitter GABA in...
4.
Lehre A, Rowley N, Zhou Y, Holmseth S, Guo C, Holen T, et al.
Epilepsy Res
. 2011 Apr;
95(1-2):70-81.
PMID: 21459558
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain. Once released, it is removed from the extracellular space by cellular uptake catalyzed by GABA transporter proteins. Four...
5.
Holmseth S, Scott H, Real K, Lehre K, Leergaard T, Bjaalie J, et al.
Neuroscience
. 2009 Mar;
162(4):1055-71.
PMID: 19328838
The neurotransmitter glutamate is inactivated by cellular uptake; mostly catalyzed by the glutamate transporter GLT1 (slc1a2, excitatory amino acid transporter [EAAT2]) subtype which is expressed at high levels in brain...
6.
Furness D, Dehnes Y, Akhtar A, Rossi D, Hamann M, Grutle N, et al.
Neuroscience
. 2008 Sep;
157(1):80-94.
PMID: 18805467
The relative distribution of the excitatory amino acid transporter 2 (EAAT2) between synaptic terminals and astroglia, and the importance of EAAT2 for the uptake into terminals is still unresolved. Here...
7.
Bjornsen L, Eid T, Holmseth S, Danbolt N, Spencer D, De Lanerolle N
Neurobiol Dis
. 2006 Nov;
25(2):319-30.
PMID: 17112731
Temporal lobe epilepsy (TLE) with hippocampal sclerosis is associated with high extracellular glutamate levels, which could trigger seizures. Down-regulation of glial glutamate transporters GLAST (EAAT1) and GLT-1 (EAAT2) in sclerotic...
8.
Holmseth S, Lehre K, Danbolt N
Anat Embryol (Berl)
. 2006 Jan;
211(4):257-66.
PMID: 16435108
Antibodies have been in widespread use for more than three decades as invaluable tools for the specific detection of proteins or other molecules in biological samples. In spite of such...
9.
Holmseth S, Dehnes Y, Bjornsen L, Boulland J, Furness D, Bergles D, et al.
Neuroscience
. 2005 Dec;
136(3):649-60.
PMID: 16344142
Unlabelled: Specific antibodies are essential tools for identifying individual proteins in biological samples. While generation of antibodies is often straightforward, determination of the antibody specificity is not. Here we illustrate...
10.
Eid T, Thomas M, Spencer D, Runden-Pran E, Lai J, Malthankar G, et al.
Lancet
. 2004 Jan;
363(9402):28-37.
PMID: 14723991
Background: High extracellular glutamate concentrations have been identified as a likely trigger of epileptic seizures in mesial temporal lobe epilepsy (MTLE), but the underlying mechanism remains unclear. We investigated whether...