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N Bernoud-Hubac

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Articles 7
Citations 205
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Recent Articles
1.
Guichardant M, Chen P, Liu M, Lo Van A, Jouvene C, Bernoud-Hubac N, et al.
Prostaglandins Leukot Essent Fatty Acids . 2020 Oct; 162:102185. PMID: 33038835
Double lipoxygenation of polyunsaturated fatty acids having at least three methylene-interrupted double bonds can be made by two lipoxygenases, e.g. 5- and 12-LOX, or 15-LOX only, followed by reduction of...
2.
Lagarde M, Calzada C, Jouvene C, Bernoud-Hubac N, Letisse M, Guichardant M, et al.
Prog Lipid Res . 2015 Oct; 60:41-9. PMID: 26484703
Synthesis of bioactive oxygenated metabolites of polyunsaturated fatty acids and their degradation or transformation products are made through multiple enzyme processes. The kinetics of the enzymes responsible for the different...
3.
Lagarde M, Hachem M, Bernoud-Hubac N, Picq M, Vericel E, Guichardant M
Prostaglandins Leukot Essent Fatty Acids . 2014 Mar; 92:63-5. PMID: 24582148
1-acetyl,2-docosahexaenoyl-glycerophosphocholine (AceDoPC) has been made to prevent docosahexaenoyl (DHA) to move to the sn-1 position as it rapidly does when present in 1-lyso,2-docosahexaenoyl-GPC (lysoPC-DHA), an efficient DHA transporter to the...
4.
Soares A, Guichardant M, Cozzone D, Bernoud-Hubac N, Bouzaidi-Tiali N, Lagarde M, et al.
Free Radic Biol Med . 2005 Mar; 38(7):882-9. PMID: 15749384
Obesity is an increasing nutritional disorder in developed countries, and oxidative stress has been identified as a key factor in numerous pathologies such as diabetes, inflammation, and atherosclerosis, which are...
5.
Guichardant M, Bernoud-Hubac N, Chantegrel B, Deshayes C, Lagarde M
Prostaglandins Leukot Essent Fatty Acids . 2002 Sep; 67(2-3):147-9. PMID: 12324234
4-Hydroxy-nonenal (4-HNE) is a major by-product of n-6 fatty acid peroxidation. It has been described to covalently bind biomolecules expressing primary amine, especially the Lys residues in proteins. Low-density lipoproteins...
6.
Bernoud-Hubac N, Davies S, Boutaud O, Montine T, Roberts 2nd L
J Biol Chem . 2001 Jun; 276(33):30964-70. PMID: 11413140
Neuroprostanes are prostaglandin-like compounds produced by free radical-induced peroxidation of docosahexaenoic acid, which is highly enriched in the brain. We previously described the formation of highly reactive gamma-ketoaldehydes (isoketals) as...
7.
Roepman R, Bernoud-Hubac N, Schick D, Maugeri A, Berger W, Ropers H, et al.
Hum Mol Genet . 2000 Aug; 9(14):2095-105. PMID: 10958648
Mutations in the retinitis pigmentosa GTPase regulator (RPGR) gene cause X-linked retinitis pigmentosa type 3 (RP3), a severe, progressive and degenerative retinal dystrophy eventually leading to complete blindness. RPGR is...