N Aboul-Ela
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Explore the profile of N Aboul-Ela including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
230
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Recent Articles
1.
El-Kahawy R, El-Shafeiy M, Helal S, Aboul-Ela N, El-Wahab M
Environ Monit Assess
. 2018 Apr;
190(5):312.
PMID: 29705964
The Red Sea encompasses a wide range of tropical marine habitats that are stressed due to anthropogenic activities. The main anthropogenic activities are hydrocarbon exploration and important trading harbors. This...
2.
Lin W, Ame J, Aboul-Ela N, Jacobson E, Jacobson M
J Biol Chem
. 1997 May;
272(18):11895-901.
PMID: 9115250
The synthesis and rapid turnover of ADP-ribose polymers is an immediate cellular response to DNA damage. We report here the isolation and characterization of cDNA encoding poly(ADP-ribose) glycohydrolase (PARG), the...
3.
Slama J, Aboul-Ela N, Jacobson M
J Med Chem
. 1995 Oct;
38(21):4332-6.
PMID: 7473561
Adenosine diphosphate (hydroxymethyl)pyrrolidinediol (ADP-HPD), a nitrogen-in-the-ring analog of ADP-ribose, was recently shown to be a potent and specific inhibitor of poly(ADP-ribose) glycohydrolase. Analysis of the inhibition kinetics of the hydrolase...
4.
Slama J, Aboul-Ela N, Goli D, Cheesman B, Simmons A, Jacobson M
J Med Chem
. 1995 Jan;
38(2):389-93.
PMID: 7830282
Adenosine diphosphate (hydroxymethyl)pyrrolidinediol (ADP-HPD), an NH analog of ADP-ribose, was chemically synthesized and shown to be a potent and specific inhibitor of poly-(ADP-ribose) glycohydrolase. The synthetic starting material was the...
5.
Witmer M, Aboul-Ela N, Jacobson M, Stamato T
Mutat Res
. 1994 May;
314(3):249-60.
PMID: 7513057
Using a replica-plating procedure and a 32P-NAD+ permeable cell-screening assay, we have isolated a CHO mutant, PADR-9, which displays approximately 17% of the wild-type level of poly(ADP-ribose) polymerase activity. Biochemical...
6.
Hanson K, Aboul-Ela N, Jacobson M, Wu M
Arch Biochem Biophys
. 1993 Apr;
302(1):193-9.
PMID: 7682390
A set of membrane proteins from murine myelomonocytic leukemia cell line WEHI-3BD+ was found to be ADP-ribosylated. Both this ADP-ribosylation reaction and granulocytic differentiation in response to recombinant G-CSF were...
7.
Kiehlbauch C, Aboul-Ela N, Jacobson E, Ringer D, Jacobson M
Anal Biochem
. 1993 Jan;
208(1):26-34.
PMID: 8434792
Methods are described for the high resolution fractionation and characterization of ADP-ribose polymers. Polymers prepared in vitro using purified poly(ADP-ribose) polymerase were isolated free from interfering nucleic acids and salts...
8.
Blaho J, Michael N, Kang V, Aboul-Ela N, Smulson M, Jacobson M, et al.
J Virol
. 1992 Nov;
66(11):6398-407.
PMID: 1328673
Infected-cell protein 4 (ICP4), the major regulatory protein in herpes simplex viruses 1 and 2, was previously reported to accept 32P from [32P]NAD in isolated nuclei. This modification was attributed...
9.
Thomassin H, Jacobson M, Guay J, Verreault A, Aboul-Ela N, Menard L, et al.
Nucleic Acids Res
. 1990 Aug;
18(16):4691-4.
PMID: 2395636
The preparation of quantities of poly(ADP-ribose) glycohydrolase sufficient for detailed structural and enzymatic characterizations has been difficult due to the very low tissue content of the enzyme and its lability...
10.
Jacobson M, Loflin P, Aboul-Ela N, Mingmuang M, Moss J, Jobson E
J Biol Chem
. 1990 Jul;
265(19):10825-8.
PMID: 2113525
Proteins can be post-translationally modified by ADP-ribose. Previously, two classes of ADP-ribosyl protein linkages have been detected in vivo which have chemical properties indistinguishable from ADP-ribosyl arginine and ADP-ribosyl glutamate...