N A Timchenko
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Explore the profile of N A Timchenko including associated specialties, affiliations and a list of published articles.
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34
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1234
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Recent Articles
1.
Nelsen C, Rickheim D, Timchenko N, Stanley M, Albrecht J
Cancer Res
. 2001 Dec;
61(23):8564-8.
PMID: 11731443
Cyclin D1 regulates mitogen-dependent progression through G(1) phase in cultured cells, and its overexpression in malignant cells is thought to contribute to autonomous proliferation in vivo. However, previous studies in...
2.
Wang H, Iakova P, Wilde M, Welm A, Goode T, Roesler W, et al.
Mol Cell
. 2001 Oct;
8(4):817-28.
PMID: 11684017
The transcription factor CCAAT/enhancer binding protein alpha (C/EBPalpha) is a strong inhibitor of cell proliferation. We found that C/EBPalpha directly interacts with cdk2 and cdk4 and arrests cell proliferation by...
3.
Timchenko N, Iakova P, Cai Z, Smith J, Timchenko L
Mol Cell Biol
. 2001 Sep;
21(20):6927-38.
PMID: 11564876
Differentiation of skeletal muscle is affected in myotonic dystrophy (DM) patients. Analysis of cultured myoblasts from DM patients shows that DM myoblasts lose the capability to withdraw from the cell...
4.
Timchenko N, Cai Z, Welm A, Reddy S, Ashizawa T, Timchenko L
J Biol Chem
. 2000 Dec;
276(11):7820-6.
PMID: 11124939
An RNA CUG triplet repeat binding protein, CUGBP1, regulates splicing and translation of various RNAs. Expansion of RNA CUG repeats in the 3'-untranslated repeat of the mutant myotonin protein kinase...
5.
Welm A, Mackey S, Timchenko L, Darlington G, Timchenko N
J Biol Chem
. 2000 Jun;
275(35):27406-13.
PMID: 10854425
Lipopolysacharide (LPS) induced acute phase response (APR) in mouse liver leads to elevation of the low molecular weight CCAAT/Enhancer binding protein (C/EBP) beta isoform, liver-enriched transcriptional inhibitory protein (LIP). In...
6.
Timchenko N, Welm A, Lu X, Timchenko L
Nucleic Acids Res
. 1999 Oct;
27(22):4517-25.
PMID: 10536163
The transcription factor CCAAT/enhancer binding protein beta, C/EBPbeta, plays a significant role in the regulation of hepatocyte growth and differentiation. A single mRNA coding for C/EBPbeta produces several protein isoforms....
7.
Timchenko N, Wilde M, Iakova P, Albrecht J, Darlington G
Nucleic Acids Res
. 1999 Aug;
27(17):3621-30.
PMID: 10446255
We have previously found that loss of C/EBPalpha in hepatocytes of newborn livers leads to increased proliferation, to a reduction in p21 protein levels and to an induction of S...
8.
Timchenko N, Wilde M, Darlington G
Mol Cell Biol
. 1999 Mar;
19(4):2936-45.
PMID: 10082561
We previously showed that the rate of hepatocyte proliferation in livers from newborn C/EBPalpha knockout mice was increased. An examination of cell cycle-related proteins showed that the cyclin-dependent kinase (CDK)...
9.
Welm A, Timchenko N, Darlington G
Mol Cell Biol
. 1999 Feb;
19(3):1695-704.
PMID: 10022857
C/EBPalpha and C/EBPbeta are intronless genes that can produce several N-terminally truncated isoforms through the process of alternative translation initiation at downstream AUG codons. C/EBPbeta has been reported to produce...
10.
Timchenko N, Darlington G
Hepatology
. 1999 Jan;
29(2):597-601.
PMID: 9918941
Both CCAAT/enhancer binding protein alpha (C/EBPalpha) and C/EBPbeta are intronless, yet can create various N-terminally truncated protein products with distinct DNA binding and transactivation potentials. These proteins can be generated...