Myron L Toews
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Explore the profile of Myron L Toews including associated specialties, affiliations and a list of published articles.
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49
Citations
532
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Recent Articles
1.
Huang Y, Xie Y, Abel P, Wei P, Plowman J, Toews M, et al.
Biochem Pharmacol
. 2020 Jul;
180:114172.
PMID: 32712053
Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial lung disease with irreversible loss of lung tissue and function. Myofibroblasts in the lung are key cellular mediators of IPF progression. Transforming...
2.
Nunez F, Schulte N, Fogel D, Michalski J, Rennard S, Penn R, et al.
Naunyn Schmiedebergs Arch Pharmacol
. 2019 Dec;
393(5):843-856.
PMID: 31884570
Pulmonary fibrosis is characterized by fibroblasts persisting in an activated form, producing excessive fibrous material that destroys alveolar structure. The second messenger molecule cyclic 3',5'-adenosine monophosphate (cAMP) has antifibrotic properties,...
3.
Mustoe A, Schulte N, Taylor J, French J, Toews M
Sci Rep
. 2019 Oct;
9(1):15480.
PMID: 31664130
Oxytocin (OXT) is an important neuromodulator of social behaviors via activation of both oxytocin receptors (OXTR) and vasopressin (AVP) 1a receptors (AVPR1a). Marmosets are neotropical primates with a modified OXT...
4.
Dodmane P, Schulte N, Heires A, Band H, Romberger D, Toews M
Exp Lung Res
. 2019 Mar;
44(10):443-454.
PMID: 30862200
Purpose Of The Study: Workers in enclosed hogbarns experience an increased incidence of airway inflammation and obstructive lung disease, and an aqueous hogbarn dust extract (HDE) induces multiple inflammation-related responses...
5.
Taylor J, Schulte N, French J, Toews M
J Pharmacol Exp Ther
. 2018 Aug;
367(1):101-107.
PMID: 30068728
A clade of New World monkeys (NWMs) exhibits considerable diversity in both oxytocin (OT) ligand and oxytocin receptor (OTR) structure. Most notable is the variant Pro-OT, with proline instead of...
6.
Nordgren T, Heires A, Bailey K, Katafiasz D, Toews M, Wichman C, et al.
Am J Physiol Lung Cell Mol Physiol
. 2017 Nov;
314(3):L421-L431.
PMID: 29097425
Injurious dust exposures in the agricultural workplace involve the release of inflammatory mediators and activation of epidermal growth factor receptor (EGFR) in the respiratory epithelium. Amphiregulin (AREG), an EGFR ligand,...
7.
Ng T, Toews M
World J Cardiol
. 2016 Nov;
8(10):584-589.
PMID: 27847559
Aim: To evaluate the effect of norepinephrine on inflammatory cytokine expression in human monocytes and monocytic THP-1 cells. Methods: For human monocyte studies, cells were isolated from 12 chronic heart...
8.
Xie Y, Jiang H, Zhang Q, Mehrotra S, Abel P, Toews M, et al.
Respir Res
. 2016 Aug;
17(1):103.
PMID: 27549302
Background: Pirfenidone was recently approved for treatment of idiopathic pulmonary fibrosis. However, the therapeutic dose of pirfenidone is very high, causing side effects that limit its doses and therapeutic effectiveness....
9.
Romberger D, Heires A, Nordgren T, Poole J, Toews M, West W, et al.
Am J Physiol Lung Cell Mol Physiol
. 2016 May;
311(1):L101-10.
PMID: 27190062
Agricultural dust exposure results in significant lung inflammation, and individuals working in concentrated animal feeding operations (CAFOs) are at risk for chronic airway inflammatory diseases. Exposure of bronchial epithelial cells...
10.
Romberger D, Heires A, Nordgren T, Souder C, West W, Liu X, et al.
Am J Physiol Lung Cell Mol Physiol
. 2015 Jun;
309(4):L388-99.
PMID: 26092994
Workers exposed to aerosolized dust present in concentrated animal feeding operations (CAFOs) are susceptible to inflammatory lung diseases, such as chronic obstructive pulmonary disease. Extracts of dust collected from hog...