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Mylene Bohec

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Articles 28
Citations 1099
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Recent Articles
1.
Croizer H, Mhaidly R, Kieffer Y, Gentric G, Djerroudi L, Leclere R, et al.
Nat Commun . 2024 Apr; 15(1):2806. PMID: 38561380
Although heterogeneity of FAP+ Cancer-Associated Fibroblasts (CAF) has been described in breast cancer, their plasticity and spatial distribution remain poorly understood. Here, we analyze trajectory inference, deconvolute spatial transcriptomics at...
2.
Licaj M, Mhaidly R, Kieffer Y, Croizer H, Bonneau C, Meng A, et al.
Nat Commun . 2024 Feb; 15(1):1312. PMID: 38346978
Although cancer-associated fibroblast (CAF) heterogeneity is well-established, the impact of chemotherapy on CAF populations remains poorly understood. Here we address this question in high-grade serous ovarian cancer (HGSOC), in which...
3.
Al Zouabi L, Stefanutti M, Roumeliotis S, Le Meur G, Boumard B, Riddiford N, et al.
Cell Rep . 2023 Nov; 42(12):113485. PMID: 38032794
During development and aging, genome mutation leading to loss of heterozygosity (LOH) can uncover recessive phenotypes within tissue compartments. This phenomenon occurs in normal human tissues and is prevalent in...
4.
Sylvestre M, Barbier N, Sibut V, Nayar S, Monvoisin C, Leonard S, et al.
Sci Adv . 2023 Nov; 9(48):eadh2708. PMID: 38019914
Mature lymphoid stromal cells (LSCs) are key organizers of immune responses within secondary lymphoid organs. Similarly, inflammation-driven tertiary lymphoid structures depend on immunofibroblasts producing lymphoid cytokines and chemokines. Recent studies...
5.
Lobon-Iglesias M, Andrianteranagna M, Han Z, Chauvin C, Masliah-Planchon J, Manriquez V, et al.
Nat Commun . 2023 Oct; 14(1):6669. PMID: 37863903
Atypical teratoid rhabdoid tumors (ATRT) are divided into MYC, TYR and SHH subgroups, suggesting diverse lineages of origin. Here, we investigate the imaging of human ATRT at diagnosis and the...
6.
Gentien D, Saberi-Ansari E, Servant N, Jolly A, De La Grange P, Nemati F, et al.
Cell Rep . 2023 Sep; 42(9):113132. PMID: 37708024
Uveal melanoma (UM) is a rare cancer resulting from the transformation of melanocytes in the uveal tract. Integrative analysis has identified four molecular and clinical subsets of UM. To improve...
7.
Calugareanu A, Specque F, Demouche S, Grolleau C, Dobos G, Merandet M, et al.
J Invest Dermatol . 2023 Jun; 143(12):2525-2529.e5. PMID: 37263486
No abstract available.
8.
Passeri T, Gutman T, Hamza A, Adle-Biassette H, Girard E, Beaurepere R, et al.
J Neurosurg . 2023 Apr; 139(5):1270-1280. PMID: 37029667
Objective: Chordomas are rare bone neoplasms characterized by a high recurrence rate and no benefit from any approved medical treatment to date. However, the investigation of molecular alterations in chordomas...
9.
Burbage M, Rocanin-Arjo A, Baudon B, Arribas Y, Merlotti A, Rookhuizen D, et al.
Sci Immunol . 2023 Feb; 8(80):eabm6360. PMID: 36735776
Oncogenesis often implicates epigenetic alterations, including derepression of transposable elements (TEs) and defects in alternative splicing. Here, we explore the possibility that noncanonical splice junctions between exons and TEs represent...
10.
Costa A, Thirant C, Kramdi A, Pierre-Eugene C, Louis-Brennetot C, Blanchard O, et al.
J Immunother Cancer . 2022 Sep; 10(8). PMID: 36054452
Background: High-risk neuroblastoma is a pediatric cancer with still a dismal prognosis, despite multimodal and intensive therapies. Tumor microenvironment represents a key component of the tumor ecosystem the complexity of...