My Hedhammar
Overview
Explore the profile of My Hedhammar including associated specialties, affiliations and a list of published articles.
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Articles
65
Citations
1716
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Recent Articles
1.
Pasupuleti R, Jansson R, Isacsson I, Hogan F, Widhe M, Hedhammar M
ACS Omega
. 2025 Feb;
10(6):5943-5952.
PMID: 39989757
Functionalization of biomaterials with extra protein domains will expand their functional roles in biomedical research. The recombinant spider silk protein FN-4RepCT has been shown able to adapt various formats like...
2.
Teworte S, Behrens M, Widhe M, Gurzeler L, Hedhammar M, Luciani P
Small
. 2025 Feb;
:e2409126.
PMID: 39967482
This study advances sustainable pharmaceutical research for endometriosis by developing in vitro 3D cell culture models of endometriotic pathophysiology that allow antifibrotic drug candidates to be tested. Fibrosis is a...
3.
Gustafsson L, Gkouma S, Jonsson A, Dufva M, Hedhammar M
J Vis Exp
. 2024 Nov;
(213).
PMID: 39555807
Replicating tissue barriers is critical for generating relevant in vitro models for evaluating novel therapeutics. Today, this is commonly done using tissue culture inserts with a plastic membrane, which generates...
4.
Gkouma S, Bhalla N, Frapard S, Jonsson A, Gurbuz H, Dogan A, et al.
Biofabrication
. 2024 Oct;
17(1).
PMID: 39454592
Physiologically relevant human skin models that include key skin cell types can be used fordrug testing, skin pathology studies, or clinical applications such as skin grafts. However, there is still...
5.
De Oliveira D, Gowda V, Sparrman T, Gustafsson L, Sanches Pires R, Riekel C, et al.
Nat Commun
. 2024 May;
15(1):4670.
PMID: 38821983
The major ampullate Spidroin 1 (MaSp1) is the main protein of the dragline spider silk. The C-terminal (CT) domain of MaSp1 is crucial for the self-assembly into fibers but the...
6.
Collodet C, Blust K, Gkouma S, Stahl E, Chen X, Hartman J, et al.
Bioeng Transl Med
. 2023 Sep;
8(5):e10537.
PMID: 37693069
Traditional cancer models rely on 2D cell cultures or 3D spheroids, which fail to recapitulate cell-extracellular matrix (ECM) interactions, a key element of tumor development. Existing hydrogel-based 3D alternatives lack...
7.
Ornithopoulou E, Astrand C, Gustafsson L, Crouzier T, Hedhammar M
ACS Appl Bio Mater
. 2023 Aug;
6(9):3696-3705.
PMID: 37579070
Biomaterials made of self-assembling protein building blocks are widely explored for biomedical applications, for example, as drug carriers, tissue engineering scaffolds, and functionalized coatings. It has previously been shown that...
8.
Hjelm L, Hedhammar M, Lofblom J
Biochem Biophys Res Commun
. 2023 Jun;
669:77-84.
PMID: 37267863
The blood-brain barrier (BBB) limits the uptake of central nervous system (CNS)-targeting drugs into the brain. Engineering molecular shuttles for active transportation across the barrier has thus potential for improving...
9.
De Oliveira D, Biler M, Mim C, Enstedt L, Kvick M, Norman P, et al.
ACS Appl Bio Mater
. 2023 Feb;
6(3):1011-1018.
PMID: 36791416
A detailed insight about the molecular organization behind spider silk assembly is valuable for the decoding of the unique properties of silk. The recombinant partial spider silk protein 4RepCT contains...
10.
Gustafsson L, Kvick M, Astrand C, Ponsteen N, Dorka N, Hegrova V, et al.
Macromol Biosci
. 2023 Jan;
23(4):e2200450.
PMID: 36662774
Elongated protein-based micro- and nanostructures are of great interest for a wide range of biomedical applications, where they can serve as a backbone for surface functionalization and as vehicles for...