Mutsuko Hirata-Koizumi
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Explore the profile of Mutsuko Hirata-Koizumi including associated specialties, affiliations and a list of published articles.
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48
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247
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Recent Articles
11.
Hasegawa R, Hirata-Koizumi M, Dourson M, Parker A, Ono A, Hirose A
Regul Toxicol Pharmacol
. 2012 Nov;
65(1):108-14.
PMID: 23137930
The available toxicity information for boron was reevaluated and four appropriate toxicity studies were selected in order to derive a tolerable daily intake (TDI) using newly proposed uncertainty factors (UFs)...
12.
Matsumoto M, Serizawa H, Sunaga M, Kato H, Takahashi M, Hirata-Koizumi M, et al.
J Toxicol Sci
. 2012 Jun;
37(3):463-74.
PMID: 22687986
Three female Crl:CD(SD) rats/group were dosed with single wall carbon nanotube (SWCNT) or multi wall carbon nanotube (MWCNT) four times by gavage at a total of 50 mg/kg bw or...
13.
Takahashi M, Kato H, Doi Y, Hagiwara A, Hirata-Koizumi M, Ono A, et al.
J Toxicol Sci
. 2012 Apr;
37(2):353-61.
PMID: 22467026
To obtain initial information on the possible repeated-dose oral toxicity of fullerene C60, Crl:CD(SD) rats were administered fullerene C60 by gavage once daily at 0 (vehicle: corn oil), 1, 10,...
14.
Hirata-Koizumi M, Fujii S, Furukawa M, Ono A, Hirose A
J Toxicol Sci
. 2012 Feb;
37(1):63-79.
PMID: 22293412
Male and female rats were given perfluorooctadecanoic acid (PFOdA) by gavage at 40, 200 or 1,000 mg/kg/day, and each female was mated with a male in the same dose group...
15.
Hirata-Koizumi M, Fujii S, Ono A, Hirose A, Imai T, Ogawa K, et al.
Food Chem Toxicol
. 2011 May;
49(9):1948-59.
PMID: 21570446
Aluminium ammonium sulfate (AAS) was tested for reproductive/developmental toxicity in a two-generation study. Male and female rats were continuously given AAS in drinking water at 0, 50, 500 or 5000...
16.
Hirata-Koizumi M, Fujii S, Ono A, Hirose A, Imai T, Ogawa K, et al.
Reprod Toxicol
. 2010 Nov;
31(2):219-30.
PMID: 21094250
In a two-generation reproductive toxicity study, male and female rats were given aluminium sulfate (AS) in drinking water at 0, 120, 600 or 3000 ppm. AS reduced water consumption in...
17.
Hasegawa R, Hirata-Koizumi M, Dourson M, Parker A, Sweeney L, Nishikawa A, et al.
Regul Toxicol Pharmacol
. 2010 Jun;
58(2):237-42.
PMID: 20561553
We propose new uncertainty factors (UFs) and a new subdivision of default factors in chemical risk assessment using a probabilistic approach based on the latest applicable information. Rounded values of...
18.
Hirata-Koizumi M, Matsuyama T, Imai T, Hirose A, Kamata E, Ema M
Congenit Anom (Kyoto)
. 2009 Dec;
49(4):247-52.
PMID: 20021483
2-(2'-hydroxy-3',5'-di-tert-butylphenyl)benzotriazole (HDBB) is an ultraviolet absorber used in plastic resin products, such as building materials and automobile components. In oral repeated dose toxicity studies using 5- or 6-week-old rats, this...
19.
Ema M, Ise R, Kato H, Oneda S, Hirose A, Hirata-Koizumi M, et al.
Reprod Toxicol
. 2009 Sep;
29(1):49-56.
PMID: 19751816
The present study was performed to determine experimental conditions for thalidomide induction of fetal malformations and to understand the molecular mechanisms underlying thalidomide teratogenicity in cynomolgus monkeys. Cynomolgus monkeys were...
20.
Hirata-Koizumi M, Matsuno K, Kawabata M, Yajima K, Matsuyama T, Hirose A, et al.
Drug Chem Toxicol
. 2009 Jun;
32(3):204-14.
PMID: 19538016
Previously, we showed that the toxic susceptibility of male rats to an ultraviolet absorber, 2-(2'-hydroxy- 3',5'-di-tert-butylphenyl)benzotriazole (HDBB), was nearly 25 times higher than that of females. The present study aimed...