Murat Digicaylioglu
Overview
Explore the profile of Murat Digicaylioglu including associated specialties, affiliations and a list of published articles.
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25
Citations
844
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Recent Articles
11.
Scranton R, Fletcher L, Sprague S, Jimenez D, Digicaylioglu M
PLoS One
. 2011 May;
6(4):e18711.
PMID: 21533252
Background: The blood brain barrier (BBB) is impermeable to most drugs, impeding the establishment of novel neuroprotective therapies and strategies for many neurological diseases. Intranasal administration offers an alternative path...
12.
Obenaus A, Dilmac N, Tone B, Tian H, Hartman R, Digicaylioglu M, et al.
Ann Neurol
. 2011 Mar;
69(2):282-91.
PMID: 21387373
Objective: Quantitative magnetic resonance imaging (MRI) can serially and noninvasively assess the degree of injury in rat pup models of hypoxic ischemic injury (HII). It can also noninvasively monitor stem...
13.
Temporal differences in microRNA expression patterns in astrocytes and neurons after ischemic injury
Ziu M, Fletcher L, Rana S, Jimenez D, Digicaylioglu M
PLoS One
. 2011 Mar;
6(2):e14724.
PMID: 21373187
MicroRNAs (miRNAs) are small, non-protein-coding RNA molecules that modulate gene translation. Their expression is altered in many central nervous system (CNS) injuries suggesting a role in the cellular response to...
14.
Genc S, Zadeoglulari Z, Oner M, Genc K, Digicaylioglu M
Expert Opin Drug Deliv
. 2010 Dec;
8(1):19-32.
PMID: 21143002
Importance Of The Field: Erythropoietin (EPO) is a growth hormone and cytokine that plays an important role in erythropoiesis and neuroprotection. However, EPO treatment for neurological diseases requires repeated injections...
15.
Kang Y, Digicaylioglu M, Russo R, Kaul M, Achim C, Fletcher L, et al.
Ann Neurol
. 2010 Sep;
68(3):342-52.
PMID: 20818790
Objective: Prolonged human immunodeficiency virus-1 (HIV-1) infection leads to neurological debilitation, including motor dysfunction and frank dementia. Although pharmacological control of HIV infection is now possible, HIV-associated neurocognitive disorders (HAND)...
16.
Ghezzi P, Bernaudin M, Bernaudinb M, Bianchi R, Bianchic R, Blomgren K, et al.
Lancet
. 2010 Jul;
375(9732):2142.
PMID: 20609950
No abstract available.
17.
Digicaylioglu M
Expert Opin Biol Ther
. 2010 Apr;
10(6):937-49.
PMID: 20394473
Importance Of The Field: Recombinant erythropoietin (rEPO) failed in a recent clinical study to protect from damages induced by ischemic stroke. The lack of acute treatments in ischemic stroke and...
18.
Fletcher L, Kohli S, Sprague S, Scranton R, Lipton S, Parra A, et al.
J Neurosurg
. 2009 Mar;
111(1):164-70.
PMID: 19284235
Object: Individually, the cytokines erythropoietin (EPO) and insulin-like growth factor-I (IGF-I) have both been shown to reduce neuronal damage significantly in rodent models of cerebral ischemia. The authors have previously...
19.
Alajajian B, Fletcher L, Isgor E, Jimenez D, Digicaylioglu M
Neuroreport
. 2009 Mar;
20(6):579-83.
PMID: 19276999
3'-phosphoinositide-dependent protein kinase-1 (PDK-1) is a crucial serine/threonine kinase in the insulin-like growth factor-I (IGF-I)/AKT signaling pathway, but its function and localization in the nervous system has not been fully...
20.
Langford D, Hurford R, Hashimoto M, Digicaylioglu M, Masliah E
BMC Neurosci
. 2005 Feb;
6:8.
PMID: 15689238
Background: The blood brain barrier (BBB) is the first line of defence of the central nervous system (CNS) against circulating pathogens, such as HIV. The cytotoxic HIV protein, gp120, damages...