Munjal M Acharya
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Explore the profile of Munjal M Acharya including associated specialties, affiliations and a list of published articles.
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68
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2092
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Recent Articles
1.
Dickstein D, Zhang R, Ru N, Vozenin M, Perry B, Wang J, et al.
Brain Struct Funct
. 2025 Mar;
230(2):41.
PMID: 40024988
Evidence shows that ultra-high dose-rate FLASH-radiotherapy (FLASH-RT) provides relative protection against normal tissue complications and functional decrements in the irradiated brain. Past work has shown that radiation-induced cognitive impairment, neuroinflammation...
2.
El-Khatib S, Vagadia A, Le A, Baulch J, Ng D, Du M, et al.
Acta Neuropathol Commun
. 2024 Dec;
12(1):190.
PMID: 39696694
Cranial radiation therapy (RT) for brain cancers is often associated with the development of radiation-induced cognitive dysfunction (RICD). RICD significantly impacts the quality of life for cancer survivors, highlighting an...
3.
Ng D, Hudson C, Nguyen T, Gupta S, Koh Y, Acharya M, et al.
Neurotherapeutics
. 2024 Nov;
22(1):e00480.
PMID: 39516074
Dynamin-1 (DNM1) is crucial for synaptic activity, neurotransmission, and associative memory, positioning it as a potential biomarker of cancer-related cognitive impairment (CRCI), a neurological consequence of cancer treatment characterized by...
4.
Tsourmas K, Butler C, Kwang N, Sloane Z, Dykman K, Maloof G, et al.
bioRxiv
. 2024 Nov;
PMID: 39484433
Lysosomal storage disorders (LSDs) are a large disease class involving lysosomal dysfunction, often resulting in neurodegeneration. Sandhoff disease (SD) is an LSD caused by a deficiency in the β subunit...
5.
Hwang W, Perrault E, Birbrair A, Mattson B, Gutmann D, Mabbott D, et al.
Cancer Cell
. 2024 Oct;
43(1):1-5.
PMID: 39423816
Cancer neuroscience is a rapidly growing multidisciplinary field that conceptualizes tumors as tissues fully integrated into the nervous system. Recognizing the complexity and challenges in this field is of fundamental...
6.
El-Khatib S, Vagadia A, Le A, Ng D, Baulch J, Du M, et al.
bioRxiv
. 2024 Oct;
PMID: 39386496
Cranial radiation therapy (RT) for brain cancers is often associated with the development of radiation-induced cognitive dysfunction (RICD). RICD significantly impacts the quality of life for cancer survivors, highlighting an...
7.
Dickstein D, Zhang R, Ru N, Vozenin M, Perry B, Wang J, et al.
Res Sq
. 2024 Aug;
PMID: 39108471
Evidence shows that ultra-high dose-rate FLASH-radiotherapy (FLASH-RT) protects against normal tissue complications and functional decrements in the irradiated brain. Past work has shown that radiation-induced cognitive impairment, neuroinflammation and reduced...
8.
Krattli R, Do A, El-Khatib S, Alikhani L, Markarian M, Vagadia A, et al.
bioRxiv
. 2024 Jul;
PMID: 39005286
Significance: Cranial radiotherapy for brain cancers activates CNS complement cascade, leading to cognitive decline. Ablation of the complement C5a/C5aR1 axis alleviates radiation-induced neuroinflammation, synaptic loss, and cognitive dysfunction, providing a...
9.
Ifejeokwu O, Do A, El Khatib S, Ho N, Zavala A, Othy S, et al.
bioRxiv
. 2024 Jul;
PMID: 39005282
Significance: Despite the superior therapeutic efficacy of immune checkpoint inhibition (ICI) for cancers, its undesired effects on brain function are not fully understood. Here, we demonstrate that combination ICI elevates...
10.
Ng D, Hudson C, Nguyen T, Gupta S, Koh Y, Acharya M, et al.
bioRxiv
. 2024 Jun;
PMID: 38895481
Dynamin-1 (DNM1) consolidates memory through synaptic transmission and modulation and has been explored as a therapeutic target in Alzheimer's disease. Through a two-prong approach, this study examined its role in...