Munehisa Takahashi
Overview
Explore the profile of Munehisa Takahashi including associated specialties, affiliations and a list of published articles.
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18
Citations
474
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Recent Articles
1.
Yoshimura T, Galligan C, Takahashi M, Chen K, Liu M, Tessarollo L, et al.
Front Immunol
. 2014 Jan;
4:482.
PMID: 24432017
Monocyte chemoattractant protein-1 (MCP-1)/CCL2 is a chemokine regulating the recruitment of monocytes into sites of inflammation and cancer. MCP-1 can be produced by a variety of cell types, such as...
2.
Yamashita J, Iwamura C, Ito T, Narita M, Hara Y, Sasaki T, et al.
J Immunol
. 2013 Jun;
191(2):949-60.
PMID: 23772025
Crohn's disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract, where excessive Th1 cell responses are observed. We performed experiments to identify immunologically bioactive proteins in human plasma...
3.
Sakai H, Furihata M, Matsuda C, Takahashi M, Miyazaki H, Konakahara T, et al.
Clin Exp Metastasis
. 2012 Jan;
29(4):327-38.
PMID: 22274590
As malignant breast cancers progress, they acquire the ability to spread to other regions of the body, including bone and lung, but the molecular mechanism underlying the increase in metastatic...
4.
An P, Li R, Wang J, Yoshimura T, Takahashi M, Samudralal R, et al.
PLoS Genet
. 2011 Nov;
7(10):e1002328.
PMID: 22046140
Chromosome 3p21-22 harbors two clusters of chemokine receptor genes, several of which serve as major or minor coreceptors of HIV-1. Although the genetic association of CCR5 and CCR2 variants with...
5.
Yamashita J, Iwamura C, Mitsumori K, Hosokawa H, Sasaki T, Takahashi M, et al.
Leuk Lymphoma
. 2011 Sep;
53(3):479-86.
PMID: 21936769
Schnurri (Shn)-2 is a large zinc finger-containing protein implicated in cell growth, signal transduction and lymphocyte development. Here, we report that Shn-2-deficient (Shn-2(-/-)) mice develop CD3-positive lymphoma spontaneously. In Shn-2(-/-)...
6.
Yamashita J, Iwamura C, Sasaki T, Mitsumori K, Ohshima K, Hada K, et al.
J Immunol
. 2011 Feb;
186(6):3410-20.
PMID: 21300819
Con A-induced hepatitis has been used as a model of human autoimmune or viral hepatitis. During the process of identifying immunologically bioactive proteins in human plasma, we found that apolipoprotein...
7.
Sasaoka T, Ito M, Yamashita J, Nakajima K, Tanaka I, Narita M, et al.
Am J Physiol Gastrointest Liver Physiol
. 2011 Jan;
300(4):G568-76.
PMID: 21193526
Inflammatory bowel disease (IBD) represents a group of chronic inflammatory diseases characterized by inflammation and relapsing gastrointestinal disorders. Recent studies have shown that Th17 cells, which are well known as...
8.
Takahashi M, Galligan C, Tessarollo L, Yoshimura T
J Immunol
. 2009 Jul;
183(5):3463-71.
PMID: 19641140
MCP-1/CCL2 plays a critical role in monocyte recruitment into sites of immune responses and cancer. However, the role of other MCPs remains unclear. In this study, we generated a novel...
9.
Takahashi M, Miyazaki H, Furihata M, Sakai H, Konakahara T, Watanabe M, et al.
Clin Exp Metastasis
. 2009 Jul;
26(7):817-28.
PMID: 19629725
Bone is the most frequent site of breast cancer metastasis, and once such metastasis occurs, complete remission is extremely difficult to achieve. In an effort to define the mechanisms underlying...
10.
Takahashi M, Furihata M, Akimitsu N, Watanabe M, Kaul S, Yumoto N, et al.
Clin Exp Metastasis
. 2008 Mar;
25(5):517-29.
PMID: 18340424
To understand the mechanisms underlying bone marrow metastasis precisely, we established the highly metastatic 4T1E/M3 murine breast cancer cell line. 4T1 murine breast cancer cells were transfected with the neomycin...