Muhammet Ay
Overview
Explore the profile of Muhammet Ay including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
310
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Recent Articles
1.
Asaithambi A, Jang A, Ghosh A, Ay M, Jin H, Anantharam V, et al.
bioRxiv
. 2025 Mar;
PMID: 40027802
Oxidative stress leads to degeneration in Parkinson's disease (PD). The key signal transduction and regulatory networks that are involved during this degenerative process in PD are currently being investigated for...
2.
Abu-Salah A, Cesur M, Anchan A, Ay M, Langley M, Shah A, et al.
Environ Sci Technol
. 2024 Nov;
58(46):20525-20539.
PMID: 39499804
Exposure to PFAS such as GenX (HFPO dimer acid) has become increasingly common due to the replacement of older generation PFAS in manufacturing processes. While neurodegenerative and developmental effects of...
3.
Lai Y, Ay M, Hospital C, Miller G, Sarkar S
Environ Health Perspect
. 2024 Sep;
132(9):94201.
PMID: 39230330
Background: Significant progress has been made over the past decade in measuring the chemical components of the exposome, providing transformative population-scale frameworks in probing the etiologic link between environmental factors...
4.
Ay M, Charli A, Langley M, Jang A, Padhi P, Jin H, et al.
Front Neurosci
. 2024 Mar;
18:1356703.
PMID: 38449738
Impaired mitochondrial function and biogenesis have strongly been implicated in the pathogenesis of Parkinson's disease (PD). Thus, identifying the key signaling mechanisms regulating mitochondrial biogenesis is crucial to developing new...
5.
Ay M
Iran J Basic Med Sci
. 2023 Oct;
26(11):1320-1325.
PMID: 37886009
Objectives: Increasing evidence implicates impaired mitochondrial biogenesis as an important contributor to mitochondrial dysfunction, which plays a central role in the pathogenesis of neurodegenerative diseases including Parkinson's disease (PD). For...
6.
Ay M
Mol Biol Rep
. 2022 Mar;
49(6):4443-4449.
PMID: 35249168
Background: Mitochondrial dysfunction has been recognized as an important mechanism of neurodegeneration. Accumulating evidence now suggests that defects in mitochondrial biogenesis can cause mitochondrial dysfunction in neurodegenerative diseases such as...
7.
Langley M, Ghaisas S, Palanisamy B, Ay M, Jin H, Anantharam V, et al.
Exp Neurol
. 2021 Apr;
341:113716.
PMID: 33839143
Mitochondrial dysfunction has been implicated as a key player in the pathogenesis of Parkinson's disease (PD). The MitoPark mouse, a transgenic mitochondrial impairment model developed by specific inactivation of TFAM...
8.
Sarkar S, Nguyen H, Malovic E, Luo J, Langley M, Palanisamy B, et al.
J Clin Invest
. 2020 Jun;
130(8):4195-4212.
PMID: 32597830
Characterization of the key cellular targets contributing to sustained microglial activation in neurodegenerative diseases, including Parkinson's disease (PD), and optimal modulation of these targets can provide potential treatments to halt...
9.
Ghaisas S, Langley M, Palanisamy B, Dutta S, Narayanaswamy K, Plummer P, et al.
Neurotoxicology
. 2019 Sep;
75:186-199.
PMID: 31505196
Gastrointestinal (GI) disturbances are one of the earliest symptoms affecting most patients with Parkinson's disease (PD). In many cases, these symptoms are observed years before motor impairments become apparent. Hence,...
10.
Ngwa H, Ay M, Jin H, Anantharam V, Kanthasamy A, Kanthasamy A
Adv Neurobiol
. 2017 Sep;
18:287-301.
PMID: 28889273
Vanadium (V) is a transition metal that presents in multiple oxidation states and numerous inorganic compounds and is also an ultra-trace element considered to be essential for most living organisms....