Muhammad Umer Khan
Overview
Explore the profile of Muhammad Umer Khan including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
112
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Recent Articles
1.
Ibrahim S, Khan M, Khurram I, Ghani M, Sharifi-Rad J, Calina D
Eur J Med Res
. 2025 Mar;
30(1):169.
PMID: 40082963
Spiruchostatin A also referred to as YM753 and OBP801, a cyclic peptide-based natural product derived from Pseudomonas sp., is distinguished by its potent inhibition of Class I histone deacetylases (HDACs)....
2.
Jabeen S, Khan M, Ejaz H, Waqar S, Farhana A, Alruwaili M, et al.
PLoS One
. 2025 Mar;
20(3):e0318539.
PMID: 40036223
Candida albicans (C. albicans) is an opportunistic pathogen in immunocompromised individuals and a normal inhabitant of the oral cavity, throat, gastrointestinal tract, and genitourinary system among health populations. Our study...
3.
Khalid N, Khan M, Rehman R, Kanwal S, Zahid T, Ghani M, et al.
Sci Rep
. 2025 Feb;
15(1):4821.
PMID: 39924515
Breast cancer, a complex global health concern, has predominantly been studied for nuclear DNA variations. However, the role of mitochondrial DNA (mtDNA) haplogroups in breast cancer susceptibility, especially in Pakistan,...
4.
Ibrahim S, Khan M, Khurram I, Rehman R, Rauf A, Ahmad Z, et al.
Food Sci Nutr
. 2025 Feb;
13(2):e70011.
PMID: 39898116
Proteolysis Targeting Chimeras (PROTACs) have revolutionized cancer therapy by offering a selective and innovative approach to degrade key oncogenic proteins associated with various malignancies. These hybrid molecules exploit the ubiquitin-proteasome...
5.
Ibrahim S, Khan M, Noreen S, Firdous S, Khurram I, Rehman R, et al.
Cytotechnology
. 2025 Feb;
77(2):54.
PMID: 39897109
The long-term treatment of malignancies, particularly brain tumors, is challenged by abnormal protein expression and drug resistance. In terms of potency, selectivity, and overcoming drug resistance, Proteolysis Targeting Chimeras (PROTACs),...
6.
Khan M, Zahid T, Sabar M, Masood T, Ali Q, Han S, et al.
Sci Rep
. 2024 Dec;
14(1):31414.
PMID: 39733090
Focusing on the Yashkun population of Gilgit-Baltistan, an administrative territory in northern Pakistan, our study investigated mtDNA haplotypes as indicators of ancient gene flow and genetic diversity. Genomic DNA was...
7.
Khurram I, Khan M, Ibrahim S, Ghani M, Amin I, Falzone L, et al.
Med Oncol
. 2024 Nov;
42(1):7.
PMID: 39557802
Thapsigargin, a sesquiterpene lactone derived from Thapsia garganica L., has demonstrated mixed potential as an anticancer agent due to its potent ability to disrupt calcium signaling and induce apoptosis. This...
8.
Amjad A, Zaidi S, Khan M, Khan S
SAGE Open Med Case Rep
. 2024 Nov;
12:2050313X241288352.
PMID: 39483848
Cold agglutinin-induced hemolytic anemia presents diagnostic and management challenges, particularly in resource-limited settings like Pakistan. A 92-year-old male presented with altered consciousness, fever, weakness, and severe asthenia. Laboratory findings revealed...
9.
Khan M, Sakhawat A, Rehman R, Wali A, Ghani M, Akram A, et al.
AMB Express
. 2024 Sep;
14(1):99.
PMID: 39249658
Cystic fibrosis transmembrane conductance regulator (CFTR) protein is an ion channel found in numerous epithelia and controls the flow of water and salt across the epithelium. The aim of our...
10.
Sakhawat A, Awan S, Khan M, Shahid S, Maqbool T, Zubair H, et al.
J Taibah Univ Med Sci
. 2024 Aug;
19(4):775-789.
PMID: 39149519
Objectives: This study was conducted to evaluate the effects of vitamin C on apoptotic and proliferative genes in injured HepG2 cells. Methods: analysis was performed using molecular docking of chemical...