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Muhammad Imran Sajid

Explore the profile of Muhammad Imran Sajid including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 265
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Recent Articles
1.
Rai M, Sajid M, Moreno J, Parang K, Tiwari R
Pharmaceuticals (Basel) . 2024 Aug; 17(8). PMID: 39204188
Delivering nucleic acid therapeutics across cell membranes is a significant challenge. Cell-penetrating peptides (CPPs) containing arginine (R), tryptophan (W), and histidine (H) show promise for siRNA delivery. To improve siRNA...
2.
Sajid M, Nunez F, Amirrad F, Roosan M, Vojtko T, McCulloch S, et al.
Sci Rep . 2023 Oct; 13(1):17516. PMID: 37845304
Chronic hypoxia may have a huge impact on the cardiovascular and renal systems. Advancements in microscopy, metabolomics, and bioinformatics provide opportunities to identify new biomarkers. In this study, we aimed...
3.
Sajid M, Sultan Sheikh F, Anis F, Nasim N, Sumbria R, Nauli S, et al.
Adv Drug Deliv Rev . 2023 Jun; 199:114968. PMID: 37353152
Alzheimer's disease (AD) is a progressive neurodegenerative disease with a few FDA-approved drugs that provide modest symptomatic benefits and only two FDA-approved disease-modifying treatments for AD. The advancements in understanding...
4.
Raza A, Chohan T, Sarfraz M, Chohan T, Sajid M, Tiwari R, et al.
J Biomol Struct Dyn . 2023 Mar; 41(23):14358-14371. PMID: 36898855
Fibroblast growth factor receptors 1 (FGFR1) is an emerging target for the development of anticancer drugs. Uncontrolled expression of FGFR1 is strongly associated with a number of different types of...
5.
Mandal D, Lohan S, Sajid M, Alhazza A, Tiwari R, Parang K, et al.
Pharmaceutics . 2023 Feb; 15(2). PMID: 36839988
RNA interference (RNAi) has drawn enormous attention as a powerful tool because of its capability to interfere with mRNA and protein production. However, designing a safe and efficient delivery system...
6.
Sajid M, Mandal D, El-Sayed N, Lohan S, Moreno J, Tiwari R
Pharmaceutics . 2022 Apr; 14(4). PMID: 35456715
Recent approvals of siRNA-based products motivated the scientific community to explore siRNA as a treatment option for several intractable ailments, especially cancer. The success of approved siRNA therapy requires a...
7.
Sajid M, Lohan S, Kato S, Tiwari R
Antibiotics (Basel) . 2022 Mar; 11(3). PMID: 35326879
Bacterial resistance is a growing global concern necessitating the discovery and development of antibiotics effective against the drug-resistant bacterial strain. Previously, we reported a cyclic antimicrobial peptide [RW] containing arginine...
8.
Nasrolahi Shirazi A, Sajid M, Mandal D, Stickley D, Nagasawa S, Long J, et al.
Pharmaceuticals (Basel) . 2021 Nov; 14(11). PMID: 34832846
We have recently reported that a cyclic peptide containing five tryptophan, five arginine, and one cysteine amino acids [(WR)C], was able to produce peptide-capped gadolinium nanoparticles, [(WR)C]-GdNPs, in the range...
9.
El-Sayed N, Sajid M, Parang K, Tiwari R
Int J Biol Macromol . 2021 Oct; 191:1204-1211. PMID: 34597704
CGKRK is a well-known tumor homing peptide with significant specificity for many types of cancer tissues. Herein, we describe the synthesis of a novel drug delivery system based on dextran...
10.
Shoushtari S, Zoghebi K, Sajid M, Tiwari R, Parang K
Mol Pharm . 2021 Sep; 18(10):3909-3919. PMID: 34491768
The cell membrane properties create a significant obstacle in intracellular delivery of cell-impermeable and negatively charged molecules. Herein, we report the synthesis and biological evaluation of a novel series of...