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Mu-Rong Kao

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Articles 15
Citations 116
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Recent Articles
1.
Chang S, Karmakar Saldivar R, Kao M, Xing X, Yeh C, Shie J, et al.
Carbohydr Polym . 2024 Jul; 342:122394. PMID: 39048231
The exopolysaccharides of the Gram-positive bacterium Romboutsia ilealis have recently been shown to include (1,3;1,4)-β-D-glucans. In the present study, we examined another Clostridia bacterium Clostridium ventriculi that has long been...
2.
Kao M, Ma T, Chou H, Chang S, Cheng L, Liao K, et al.
ACS Chem Biol . 2024 Jun; 19(7):1515-1524. PMID: 38912881
Eliminating the core fucose from the -glycans of the Fc antibody segment by pathway engineering or enzymatic methods has been shown to enhance the potency of therapeutic antibodies, especially in...
3.
Kao M, Karmarkar Saldivar R, Hsieh Y
Curr Opin Biotechnol . 2024 May; 87:103145. PMID: 38781701
Plant-based expression systems have emerged as promising avenues for the production of recombinant N-linked glycoproteins. This review offers insights into the evolution and progress of plant glycoengineering. It delves into...
4.
Kao M, Parker J, Oehme D, Chang S, Cheng L, Wang D, et al.
Biochemistry . 2024 Apr; 63(9):1194-1205. PMID: 38598309
Barley (1,3;1,4)-β-d-glucanase is believed to have evolved from an ancestral monocotyledon (1,3)-β-d-glucanase, enabling the hydrolysis of (1,3;1,4)-β-d-glucans in the cell walls of leaves and germinating grains. In the present study,...
5.
Hsieh Y, Kao M, Tucker M
Carbohydr Res . 2024 Mar; 538:109103. PMID: 38555659
Callose, a linear (1,3)-β-glucan, is an indispensable carbohydrate polymer required for plant growth and development. Advances in biochemical, genetic, and genomic tools, along with specific antibodies, have significantly enhanced our...
6.
Chen T, Shyur E, Ma T, Wijeyewickrema L, Lin S, Kao M, et al.
Chembiochem . 2023 Dec; 25(3):e202300744. PMID: 38055188
Hirudins, natural sulfo(glyco)proteins, are clinical anticoagulants that directly inhibit thrombin, a key coagulation factor. Their potent thrombin inhibition primarily results from antagonistic interactions with both the catalytic and non-catalytic sites...
7.
Chang S, Kao M, Karmakar Saldivar R, Diaz-Moreno S, Xing X, Furlanetto V, et al.
Nat Commun . 2023 Jul; 14(1):4526. PMID: 37500617
(1,3;1,4)-β-D-Glucans are widely distributed in the cell walls of grasses (family Poaceae) and closely related families, as well as some other vascular plants. Additionally, they have been found in other...
8.
Hsiung S, Li J, Imre B, Kao M, Liao H, Wang D, et al.
Planta . 2023 Jan; 257(2):39. PMID: 36650257
The xyloglucans of all aquatic Araceae species examined had unusual structures compared with those of other non-commelinid monocotyledon families previously examined. The aquatic Araceae species Lemna minor was earlier shown...
9.
Li J, Hsiung S, Kao M, Xing X, Chang S, Wang D, et al.
Carbohydr Res . 2022 Sep; 521:108662. PMID: 36099721
Polygonatum odoratum is a perennial rhizomatous medicinal plant and different plant parts have been used in the treatment of various ailments. Herein, we have investigated the structural compositions of rhizome,...
10.
Wang D, Kao M, Li J, Sun P, Meng Q, Vyas A, et al.
J Agric Food Chem . 2022 Aug; 70(32):9941-9947. PMID: 35921143
To transform cellulose from biomass into fermentable sugars for biofuel production requires efficient enzymatic degradation of cellulosic feedstocks. The recently discovered family of oxidative enzymes, lytic polysaccharide monooxygenase (LPMO), has...