Mu-En Wang
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Explore the profile of Mu-En Wang including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
157
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Recent Articles
1.
Marek R, Halabi S, Wang M, McBane J, Wei J, Wang T, et al.
Vaccines (Basel)
. 2024 Nov;
12(11).
PMID: 39591176
: Androgen receptor (AR) expression and signaling are critical for the progression of prostate cancer and have been the therapeutic focus of prostate cancer for over 50 years. While a...
2.
3.
Hauck J, Moon D, Jiang X, Wang M, Zhao Y, Xu L, et al.
Commun Biol
. 2024 Jan;
7(1):9.
PMID: 38172561
There are limited therapeutic options for patients with advanced prostate cancer (PCa). We previously found that heat shock factor 1 (HSF1) expression is increased in PCa and is an actionable...
4.
Loh Z, Wang M, Wan C, Asara J, Ji Z, Chen M
Metabolites
. 2023 Aug;
13(8).
PMID: 37623882
The phosphatase and tensin homologue deleted on chromosome 10 (PTEN) tumor suppressor governs a variety of biological processes, including metabolism, by acting on distinct molecular targets in different subcellular compartments....
5.
Wang M, Chen J, Lu Y, Bawcom A, Wu J, Ou J, et al.
J Clin Invest
. 2023 Mar;
133(10).
PMID: 36928314
Inactivation of the RB1 tumor suppressor gene is common in several types of therapy-resistant cancers, including metastatic castration-resistant prostate cancer, and predicts poor clinical outcomes. Effective therapeutic strategies against RB1-deficient...
6.
Butler W, Xu L, Zhou Y, Cheng Q, Hauck J, He Y, et al.
J Pathol
. 2023 Feb;
260(1):43-55.
PMID: 36752189
Neuroendocrine (NE) cells comprise ~1% of epithelial cells in benign prostate and prostatic adenocarcinoma (PCa). However, they become enriched in hormonally treated and castration-resistant PCa (CRPC). In addition, close to...
7.
Budi Y, Li Y, Huang C, Wang M, Lin Y, Jong D, et al.
PeerJ
. 2022 Aug;
10:e13867.
PMID: 35990905
Aims: Studies have observed changes in autophagic flux in the adipose tissue of type 2 diabetes patients with obesity. However, the role of autophagy in obesity-induced insulin resistance is unclear....
8.
Huang C, Hsu H, Wang M, Hsu M, Wu L, Jong D, et al.
Sci Rep
. 2021 Jun;
11(1):12561.
PMID: 34131222
Obese men have lower circulating testosterone than men with an optimal body mass index. Elevated fatty acids (FAs) caused by obesity have been reported to suppress the steroidogenesis of Leydig...
9.
Huang C, Wang H, Wang M, Hsu M, Wu Y, Jiang Y, et al.
Sci Rep
. 2019 Nov;
9(1):17451.
PMID: 31767891
Previous studies have demonstrated the important role of kisspeptin in impaired glucose-stimulated insulin secretion (GSIS). In addition, it was reported that the activation of autophagy in pancreatic β-cells decreases insulin...
10.
Wang M, Singh B, Hsu M, Huang C, Yen P, Wu L, et al.
Sci Rep
. 2017 Oct;
7(1):13999.
PMID: 29070903
Previous studies have demonstrated that saturated fatty acids (SFAs) are more lipotoxic than unsaturated fatty acids (UFAs) in inhibiting hepatic autophagy and promoting non-alcoholic steatohepatitis (NASH). However, there have been...