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Motoki Shinohara

Explore the profile of Motoki Shinohara including associated specialties, affiliations and a list of published articles. Areas
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Citations 50
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Recent Articles
1.
Klaunig J, Shinohara M, Iwai H, Chengelis C, Kirkpatrick J, Wang Z, et al.
Toxicol Pathol . 2014 Nov; 43(2):209-20. PMID: 25377447
Perfluorohexanoic acid (PFHxA), a 6-carbon perfluoroalkyl (C6; CAS # 307-24-4), has been proposed as a replacement for the commonly used 8-carbon perfluoroalkyls: perfluorooctanoic acid and perfluorooctane sulfonate. PFHxA is not...
2.
Mertens J, Sved D, Marit G, Myers N, Stetson P, Murphy S, et al.
Int J Toxicol . 2010 Jun; 29(4):358-71. PMID: 20519691
S-111-S-WB, a mixture of perfluoro fatty acid ammonium salts (C(6)-C(13)), was administered orally to Crl:CD (SD)IGS-BR rats. Higher hepatic beta-oxidation and liver weights with hepatocellular hypertrophy were present at the...
3.
Chengelis C, Kirkpatrick J, Myers N, Shinohara M, Stetson P, Sved D
Reprod Toxicol . 2009 May; 27(3-4):400-406. PMID: 19429410
The toxicokinetics of perfluorohexanoic acid (PFHxA) and nonafluoro-1-butanesulfonic acid (PFBS) were evaluated in Sprague-Dawley rats and cynomolgus monkeys. Systemic exposure to PFHxA was lower than for PFBS following single equivalent...
4.
Chengelis C, Kirkpatrick J, Radovsky A, Shinohara M
Reprod Toxicol . 2009 May; 27(3-4):342-351. PMID: 19429405
Possible toxic effects of perfluorohexanoic acid (PFHxA) were evaluated when administered orally by gavage to rats at levels up to 200mg/kg/day for 90 days. Lower body weight gains were noted...
5.
Stump D, Holson J, Murphy S, Farr C, Schmit B, Shinohara M
Reprod Toxicol . 2007 Nov; 25(1):7-20. PMID: 18022344
S-111-S-WB (CAS No. 72968-38-8), a mixture of perfluoro fatty acid ammonium salts, was administered daily via oral gavage to 30 Crl:CD(SD) rats/sex/group at 0.025, 0.125 and 0.6mg/(kgday) over two generations...