Mostafa Khair
Overview
Explore the profile of Mostafa Khair including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
17
Citations
233
Followers
0
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Recent Articles
1.
Benyettou F, Das G, Boitet M, Varghese S, Khair M, Das A, et al.
J Am Chem Soc
. 2025 Feb;
147(10):8188-8204.
PMID: 40013936
Cryosurgery represents a transformative approach in the treatment of resistant tumors, utilizing extreme cold to selectively ablate malignant tissue. However, the clinical success of this technique is constrained by the...
2.
Mousa W, Shaikh A, Ghemrawi R, Aldulaimi M, Al Ali A, Sammani N, et al.
RSC Med Chem
. 2024 Oct;
PMID: 39479472
The prevalence of antibacterial resistance has become one of the major health threats of modern times, requiring the development of novel antibacterials. Antimicrobial peptides are a promising source of antibiotic...
3.
Ghemrawi R, Abuamer L, Kremesh S, Hussien G, Ahmed R, Mousa W, et al.
Biomedicines
. 2024 Sep;
12(9).
PMID: 39335671
Cancer immunotherapy has emerged as a transformative approach in oncology, utilizing the body's immune system to specifically target and destroy malignant cells. This review explores the scope and impact of...
4.
Benyettou F, Khair M, Prakasam T, Varghese S, Matouk Z, Alkaabi M, et al.
ACS Appl Mater Interfaces
. 2024 Sep;
16(42):56676-56695.
PMID: 39267454
This study presents the use of nanoscale covalent organic frameworks (nCOFs) conjugated with tumor-targeting peptides for the targeted therapy of triple-negative breast cancer (TNBC). While peptides have previously been used...
5.
Benyettou F, Jrad A, Matouk Z, Prakasam T, Hamoud H, Clet G, et al.
J Am Chem Soc
. 2024 Aug;
146(33):23537-23554.
PMID: 39110940
Membrane technology plays a central role in advancing separation processes, particularly in water treatment. Covalent organic frameworks (COFs) have transformative potential in this field due to their adjustable structures and...
6.
El Hajj Y, Shahin T, Dieng M, Alshaikh M, Khair M, Manikandan V, et al.
Sci Rep
. 2024 Mar;
14(1):6782.
PMID: 38514798
Pregnenolone sulfate is a steroid metabolite of the steroidogenesis precursor, pregnenolone, with similar functional properties, including immunosuppression. We recently reported an elevation in serum levels of pregnenolone sulfate in children...
7.
Ghemrawi R, Al Qassem A, Ramadan A, Aldulaymi R, Sammani N, Mousa W, et al.
PLoS One
. 2023 Jul;
18(7):e0288791.
PMID: 37506102
Protein and DNA methylation is involved in various biological functions such as signal transmission, DNA repair, and gene expression. Abnormal regulation of methyltransferases has been linked to multiple types of...
8.
Ghemrawi R, Kharaba Z, Aldulaymi R, AlBataineh N, Alghaly F, Qasem N, et al.
Int J Pharm Pract
. 2022 Aug;
30(6):534-540.
PMID: 35946835
Objectives: Over the past few decades, the accumulation of expired and unused medications in households has become a concern. Most people are unaware of how to properly dispose of unused...
9.
The Discovery of Potent SHP2 Inhibitors with Anti-Proliferative Activity in Breast Cancer Cell Lines
Ghemrawi R, Khair M, Hasan S, Aldulaymi R, AlNeyadi S, Atatreh N, et al.
Int J Mol Sci
. 2022 Apr;
23(8).
PMID: 35457286
Despite available treatments, breast cancer is the leading cause of cancer-related death. Knowing that the tyrosine phosphatase SHP2 is a regulator in tumorigenesis, developing inhibitors of SHP2 in breast cells...
10.
Al Adem K, Shanti A, Srivastava A, Homouz D, Thomas S, Khair M, et al.
Front Mol Biosci
. 2022 Apr;
9:842582.
PMID: 35372522
The cytotoxic self-aggregation of β-amyloid (Aβ) peptide and islet amyloid polypeptide (IAPP) is implicated in the pathogenesis of Alzheimer's disease (AD) and Type 2 diabetes (T2D), respectively. Increasing evidence, particularly...