Mostafa E Belghasem
Overview
Explore the profile of Mostafa E Belghasem including associated specialties, affiliations and a list of published articles.
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6
Citations
224
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Recent Articles
1.
Walker J, Richards S, Belghasem M, Arinze N, Yoo S, Tashjian J, et al.
Kidney Int
. 2020 Jan;
97(3):538-550.
PMID: 31932072
Emerging evidence in animal models of chronic kidney disease (CKD) implicates Aryl Hydrocarbon Receptor (AHR) signaling as a mediator of uremic toxicity. However, details about its tissue-specific and time-dependent activation...
2.
Kannan S, Morgan L, Liang B, Cheung M, Lin C, Mun D, et al.
Kidney Int Rep
. 2019 Jul;
4(7):955-962.
PMID: 31317118
Introduction: The number of glomeruli and glomerulosclerosis evaluated on kidney biopsy slides constitute standard components of a renal pathology report. Prevailing methods for glomerular assessment remain manual, labor intensive, and...
3.
Belghasem M, Aamar O, Roth D, Walker J, Arinze N, Richards S, et al.
Sci Rep
. 2019 May;
9(1):7168.
PMID: 31073168
The universal pathologic features implicated in the progression of chronic kidney disease (CKD) are interstitial fibrosis and tubular atrophy (IFTA). Current methods of estimating IFTA are slow, labor-intensive and fraught...
4.
Kolachalama V, Singh P, Lin C, Mun D, Belghasem M, Henderson J, et al.
Kidney Int Rep
. 2018 May;
3(2):464-475.
PMID: 29725651
Introduction: Chronic kidney damage is routinely assessed semiquantitatively by scoring the amount of fibrosis and tubular atrophy in a renal biopsy sample. Although image digitization and morphometric techniques can better...
5.
Kolachalama V, Shashar M, Alousi F, Shivanna S, Rijal K, Belghasem M, et al.
J Am Soc Nephrol
. 2018 Jan;
29(3):1063-1072.
PMID: 29343519
Individuals with CKD are particularly predisposed to thrombosis after vascular injury. Using mouse models, we recently described indoxyl sulfate, a tryptophan metabolite retained in CKD and an activator of tissue...
6.
Shashar M, Belghasem M, Matsuura S, Walker J, Richards S, Alousi F, et al.
Sci Transl Med
. 2017 Nov;
9(417).
PMID: 29167396
Chronic kidney disease (CKD/uremia) remains vexing because it increases the risk of atherothrombosis and is also associated with bleeding complications on standard antithrombotic/antiplatelet therapies. Although the associations of indolic uremic...