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Mortimer Mamelak

Explore the profile of Mortimer Mamelak including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 185
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Recent Articles
11.
Bogan R, Swick T, Mamelak M, Kovacevic-Ristanovic R, Lai C, Black J, et al.
Neurol Ther . 2016 Oct; 5(2):203-213. PMID: 27778193
Introduction: The present post hoc analysis was designed to evaluate health-related quality of life (HRQoL) using the 36-item Short Form Health Status Survey (SF-36) during an 8-week trial of sodium...
12.
Mamelak M, Swick T, Emsellem H, Montplaisir J, Lai C, Black J
Sleep Med . 2014 Dec; 16(1):52-8. PMID: 25533539
Objective: This study aimed to evaluate safety and efficacy of sodium oxybate (SXB) titrated to effect. Methods: SXB-naive patients who had participated in a randomized SXB clinical trial and had...
13.
Mamelak M
J Alzheimers Dis . 2012 May; 31(3):459-74. PMID: 22571985
A reduction in cerebral glucose utilization is one of the earliest signs of Alzheimer's disease. Although the exact cause of this reduction is not known, gathering evidence suggests that it...
14.
Mamelak M
Prog Neurobiol . 2009 Aug; 89(2):193-219. PMID: 19654034
A voluminous literature describes the relationship between disturbed sleep and depression. The breakdown of sleep is one of the cardinal features of depression and often also heralds its onset. Frequent...
15.
Mamelak M
Neurobiol Aging . 2006 Jul; 28(9):1340-60. PMID: 16837107
Although the cause of Alzheimer's disease is unknown, oxidative stress, energy depletion, excitotoxicity and vascular endothelial pathology are all considered to play a part in its pathogenesis. In reaction to...
16.
Mamelak M, Black J, Montplaisir J, Ristanovic R
Sleep . 2004 Dec; 27(7):1327-34. PMID: 15586785
Study Objectives: To measure the effect of nocturnal sodium oxybate administration on sleep architecture in patients with narcolepsy. Design: Open-label study. Setting: Four accredited sleep clinics. Participants: 25 adult patients...