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Morri E Feldman

Explore the profile of Morri E Feldman including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 874
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Recent Articles
1.
Herbert S, Huisken J, Kim T, Feldman M, Houseman B, Wang R, et al.
Science . 2009 Oct; 326(5950):294-8. PMID: 19815777
Blood vessels form de novo (vasculogenesis) or upon sprouting of capillaries from preexisting vessels (angiogenesis). With high-resolution imaging of zebrafish vascular development, we uncovered a third mode of blood vessel...
2.
Apsel B, Blair J, Gonzalez B, Nazif T, Feldman M, Aizenstein B, et al.
Nat Chem Biol . 2008 Oct; 4(11):691-9. PMID: 18849971
The clinical success of multitargeted kinase inhibitors has stimulated efforts to identify promiscuous drugs with optimal selectivity profiles. It remains unclear to what extent such drugs can be rationally designed,...
3.
Knight Z, Feldman M, Balla A, Balla T, Shokat K
Nat Protoc . 2007 Oct; 2(10):2459-66. PMID: 17947987
Phosphoinositide kinases such as PI3-kinase synthesize lipid second messengers that control diverse cellular processes. Recently, these enzymes have emerged as an important class of drug targets, and there is significant...
4.
Knight Z, Gonzalez B, Feldman M, Zunder E, Goldenberg D, Williams O, et al.
Cell . 2006 May; 125(4):733-47. PMID: 16647110
Phosphoinositide 3-kinases (PI3-Ks) are an important emerging class of drug targets, but the unique roles of PI3-K isoforms remain poorly defined. We describe here an approach to pharmacologically interrogate the...