Morena Scotece
Overview
Explore the profile of Morena Scotece including associated specialties, affiliations and a list of published articles.
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Articles
51
Citations
1503
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Recent Articles
1.
Conde-Aranda J, Scotece M, Varela-Garcia M, Torrijos-Pulpon C, Arosa L, Camba-Gomez M, et al.
Mediators Inflamm
. 2024 Oct;
2024:7264704.
PMID: 39403549
Background: Obesity is associated with an increased risk for different chronic diseases such as osteoarthritis (OA) or rheumatoid arthritis (RA). In fact, adipose tissue is now recognized as an endocrine...
2.
Scotece M, Drosten M
Trends Cancer
. 2024 Jun;
10(7):576-578.
PMID: 38866669
Approved BRAF inhibitors have shown limited clinical benefit due to recurrent disease progression. In a recent Cancer Discovery paper, Yaeger et al. show that a next-generation BRAF inhibitor, PF-07799933, has...
3.
Scotece M, Hamalainen M, Leppanen T, Vuolteenaho K, Moilanen E
Int J Mol Sci
. 2023 Mar;
24(5).
PMID: 36902103
Scleroderma is a chronic fibrotic disease, where proinflammatory and profibrotic events precede collagen accumulation. MKP-1 [mitogen-activated protein kinase (MAPK) phosphatase-1] downregulates inflammatory MAPK pathways suppressing inflammation. MKP-1 also supports Th1...
4.
Maki-Opas I, Hamalainen M, Moilanen E, Scotece M
Arthritis Res Ther
. 2023 Jan;
25(1):12.
PMID: 36698198
Background: Systemic sclerosis is a rheumatoid disease best known for its fibrotic skin manifestations called scleroderma. Alternatively activated (M2-type) macrophages are normally involved in the resolution of inflammation and wound...
5.
Scotece M, Conde-Aranda J
Int J Mol Sci
. 2022 Aug;
23(15).
PMID: 35955527
The inflammatory response is an adaptive mechanism that evolved to fight against infections and tissue damage [...].
6.
Scotece M, Vaamonde-Garcia C, Lechuga-Vieco A, Cortes A, Gomez M, Filgueira-Fernandez P, et al.
Aging (Albany NY)
. 2022 Jul;
14(15):5966-5983.
PMID: 35779570
Mitochondria and mtDNA variations contribute to specific aspects of the aging process. Here, we aimed to investigate the influence of mtDNA variation on joint damage in a model of aging...
7.
Ruiz-Fernandez C, Gonzalez-Rodriguez M, Abella V, Francisco V, Cordero-Barreal A, Ait Eldjoudi D, et al.
Lab Invest
. 2022 Apr;
102(9):989-999.
PMID: 35484291
Wnt-1 inducible signaling pathway protein 2 (WISP-2/CCN5) is a recently identified adipokine that has been described as an important mediator of canonical Wnt activation in adipogenic precursor cells. In osteoarthritis...
8.
Seoane-Collazo P, Rial-Pensado E, Estevez-Salguero A, Milbank E, Garcia-Caballero L, Rios M, et al.
Arthritis Rheumatol
. 2021 Aug;
74(2):212-222.
PMID: 34398520
Objective: To investigate whether thermogenesis and the hypothalamus may be involved in the physiopathology of experimental arthritis (EA). Methods: EA was induced in male Lewis rats by intradermal injection of...
9.
Scotece M, Rego-Perez I, Lechuga-Vieco A, Cortes A, Jimenez-Gomez M, Filgueira-Fernandez P, et al.
Sci Rep
. 2021 Apr;
11(1):9112.
PMID: 33907208
It has been suggested that mitochondrial dysfunction and mtDNA variations may contribute to osteoarthritis (OA) pathogenesis. However, the causative link to support this claim is lacking. Here, we surgically-induced OA...
10.
Conde J, Ruiz-Fernandez C, Francisco V, Scotece M, Gomez R, Lago F, et al.
Cartilage
. 2020 Jun;
13(2_suppl):925S-934S.
PMID: 32532182
Objective: Osteoarthritis (OA) is an age-related biomechanical and low-grade inflammometabolic disease of the joints and one of the costliest and disabling forms of arthritis. Studies on matrix-degrading enzymes such as...