Monique Willart
Overview
Explore the profile of Monique Willart including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
864
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Recent Articles
1.
De Kleer I, Kool M, de Bruijn M, Willart M, Van Moorleghem J, Schuijs M, et al.
Immunity
. 2016 Dec;
45(6):1285-1298.
PMID: 27939673
Allergic disease originates in early life and polymorphisms in interleukin-33 gene (IL33) and IL1RL1, coding for IL-33R and decoy receptor sST2, confer allergy risk. Early life T helper 2 (Th2)...
2.
Dullaers M, Schuijs M, Willart M, Fierens K, Van Moorleghem J, Hammad H, et al.
J Allergy Clin Immunol
. 2016 Oct;
140(1):76-88.e7.
PMID: 27746238
Background: Allergic asthma is a CD4 T2-lymphocyte driven disease characterized by airway hyperresponsiveness and eosinophilia. B cells can present antigens to CD4 T cells and produce IgE immunoglobulins that arm...
3.
Smet M, Van Hoecke L, De Beuckelaer A, Vander Beken S, Naessens T, Vergote K, et al.
Immun Inflamm Dis
. 2016 Sep;
4(3):350-61.
PMID: 27621817
Introduction: Liver X receptors (LXRs) are nuclear receptors that function as cholesterol sensors and regulate cholesterol homeostasis. High cholesterol has been recognized as a risk factor in asthma; however, the...
4.
Maelfait J, Roose K, Vereecke L, Mc Guire C, Sze M, Schuijs M, et al.
PLoS Pathog
. 2016 Jan;
12(1):e1005410.
PMID: 26815999
A20 negatively regulates multiple inflammatory signalling pathways. We here addressed the role of A20 in club cells (also known as Clara cells) of the bronchial epithelium in their response to...
5.
Naessens T, Schepens B, Smet M, Pollard C, Van Hoecke L, De Beuckelaer A, et al.
J Allergy Clin Immunol
. 2015 Nov;
137(3):700-9.e9.
PMID: 26560044
Background: Human respiratory syncytial virus (RSV) is a frequent cause of asthma exacerbations, yet the susceptibility of asthmatic patients to RSV is poorly understood. Objective: We sought to address the...
6.
Willart M, Hammad H
Curr Opin Immunol
. 2011 Nov;
23(6):772-7.
PMID: 22074731
Dendritic cells (DC) have been shown to be responsible for the initiation and maintenance of adaptive Th2 responses in asthma. It is increasingly clear that DC functions are strongly influenced...
7.
van Rijt L, Vos N, Willart M, Muskens F, Tak P, van der Horst C, et al.
Am J Respir Crit Care Med
. 2011 May;
184(3):303-11.
PMID: 21562124
Rationale: Polysensitization of patients who are allergic is a common feature. The underlying immunologic mechanism is not clear. The maturation status of dendritic cells (DCs) is considered to be important...
8.
Besnard A, Sabat R, Dumoutier L, Renauld J, Willart M, Lambrecht B, et al.
Am J Respir Crit Care Med
. 2011 Feb;
183(9):1153-63.
PMID: 21297073
Rationale: IL-22 has both proinflammatory and antiinflammatory properties. Its role in allergic lung inflammation has not been explored. Objectives: To investigate the expression and roles of IL-22 in the onset...
9.
Kuipers H, Soullie T, Hammad H, Willart M, Kool M, Hijdra D, et al.
J Leukoc Biol
. 2008 Oct;
85(1):64-70.
PMID: 18923103
Adoptive transfer of antigen-pulsed dendritic cells (DC) in the airways of mice has been used as a model system for eosinophilic airway inflammation, which allows studying the DC-specific contribution of...
10.
Gutierrez L, Nikolic T, van Dijk T, Hammad H, Vos N, Willart M, et al.
Blood
. 2007 May;
110(6):1933-41.
PMID: 17505015
Dendritic cells are key initiators and regulators of the immune response. Dendritic cell commitment and function require orchestrated regulation of transcription. Gata1 is a transcription factor expressed in several hematopoietic...