Monika Schmidt
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Explore the profile of Monika Schmidt including associated specialties, affiliations and a list of published articles.
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49
Citations
568
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Recent Articles
1.
Haleckova A, Syrova V, Joklova A, Vernerova T, Hurdalek J, Endlicher R, et al.
ACS Med Chem Lett
. 2024 Oct;
15(10):1756-1763.
PMID: 39411525
Cyclophilin D (CypD) is a mitochondrial enzyme widely accepted as a regulator of the mitochondrial permeability transition pore (mPTP). Excessive opening of mPTP is associated with mitochondrial dysfunction and the...
2.
Arias A, Neehus A, Ogishi M, Meynier V, Krebs A, Lazarov T, et al.
Nature
. 2024 Aug;
633(8029):417-425.
PMID: 39198650
Severe defects in human IFNγ immunity predispose individuals to both Bacillus Calmette-Guérin disease and tuberculosis, whereas milder defects predispose only to tuberculosis. Here we report two adults with recurrent pulmonary...
3.
Hrabinova M, Pejchal J, Hepnarova V, Muckova L, Junova L, Opravil J, et al.
Arch Toxicol
. 2024 Mar;
98(4):1135-1149.
PMID: 38446233
A-series agent A-234 belongs to a new generation of nerve agents. The poisoning of a former Russian spy Sergei Skripal and his daughter in Salisbury, England, in March 2018 led...
4.
Hanzlova M, Miskerikova M, Rotterova A, Chalupova K, Jurkova K, Hamsikova M, et al.
ACS Med Chem Lett
. 2023 Dec;
14(12):1724-1732.
PMID: 38116418
Multifunctional mitochondrial enzyme 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10) is a potential drug target for the treatment of various pathologies. The most discussed is the pathology associated with Alzheimer's disease (AD),...
5.
Diddens J, Lepennetier G, Friedrich V, Schmidt M, Brand R, Georgieva T, et al.
Neurol Neuroimmunol Neuroinflamm
. 2023 Dec;
11(1):e200185.
PMID: 38100739
Background And Objectives: The factors that drive progression in multiple sclerosis (MS) remain obscure. Identification of key properties of meningeal inflammation will contribute to a better understanding of the mechanisms...
6.
Bohlen J, Zhou Q, Philippot Q, Ogishi M, Rinchai D, Nieminen T, et al.
Cell
. 2023 Oct;
186(23):5114-5134.e27.
PMID: 37875108
Human inherited disorders of interferon-gamma (IFN-γ) immunity underlie severe mycobacterial diseases. We report X-linked recessive MCTS1 deficiency in men with mycobacterial disease from kindreds of different ancestries (from China, Finland,...
7.
Schmidt M, Vaskova M, Rotterova A, Fiandova P, Miskerikova M, Zemanova L, et al.
J Neurochem
. 2023 Jul;
167(2):154-167.
PMID: 37458164
Mitochondrial enzyme 17β-hydroxysteroid dehydrogenase type 10 (HSD10) is a potential molecular target for treatment of mitochondrial-related disorders such as Alzheimer's disease (AD). Its over-expression in AD brains is one of...
8.
Benek O, Vaskova M, Miskerikova M, Schmidt M, Andrys R, Rotterova A, et al.
Eur J Med Chem
. 2023 Jun;
258:115593.
PMID: 37390508
17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10) is a multifunctional mitochondrial enzyme and putative drug target for the treatment of various pathologies including Alzheimer's disease or some types of hormone-dependent cancer. In...
9.
Hepnarova V, Hrabinova M, Muckova L, Kucera T, Schmidt M, Dolezal R, et al.
Toxicol In Vitro
. 2022 Aug;
85:105463.
PMID: 36041654
Insecticides represent the most crucial element in the integrated management approach to malaria and other vector-borne diseases. The evolution of insect resistance to long-used substances and the toxicity of organophosphates...
10.
Jones A, McCarty M, Brito J, Noseworthy P, Cavanaugh K, Cameron K, et al.
Am Heart J
. 2022 Feb;
248:42-52.
PMID: 35218727
Background: Shared decision making (SDM) improves the likelihood that patients will receive care in a manner consistent with their priorities. To facilitate SDM, decision aids (DA) are commonly used, both...