Mong Sing Lai
Overview
Explore the profile of Mong Sing Lai including associated specialties, affiliations and a list of published articles.
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10
Citations
191
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Recent Articles
1.
Moriyama K, Lai M, Masai H
Adv Exp Med Biol
. 2018 Jan;
1042:287-310.
PMID: 29357064
Recent studies on G-quadruplex (G4) revealed crucial and conserved functions of G4 in various biological systems. We recently showed that Rif1, a conserved nuclear factor, binds to G4 present in...
2.
Lin C, Wu M, Gay S, Marjavaara L, Lai M, Hsiao W, et al.
PLoS Genet
. 2014 Oct;
10(10):e1004667.
PMID: 25275495
The influence of mono-ubiquitylation of histone H2B (H2Bub) on transcription via nucleosome reassembly has been widely documented. Recently, it has also been shown that H2Bub promotes recovery from replication stress;...
3.
Lai M, Seki M, Tada S, Enomoto T
Biochem Biophys Res Commun
. 2012 Oct;
427(3):682-6.
PMID: 23036200
Saccharomyces cerevisiae RecQ helicase (Sgs1) combines with DNA topoisomerase III (Top3) and RecQ-mediated genome instability 1 (Rmi1) to form an evolutionarily conserved complex that is required for processing homologous recombination...
4.
Lai M, Foiani M
Cell
. 2012 Jun;
149(6):1181-3.
PMID: 22682239
The ATR and ATM checkpoint kinases preserve the integrity of replicating chromosomes by preventing the reversal of stalled and terminal replication forks. Hu et al. now show that the ATR...
5.
Bermejo R, Lai M, Foiani M
Mol Cell
. 2012 Apr;
45(6):710-8.
PMID: 22464441
DNA and RNA polymerases clash along the genome as they compete for the same DNA template. Cells have evolved specialized strategies to prevent and resolve replication and transcription interference. Here,...
6.
Seki M, Lai M, Enomoto T
Tanpakushitsu Kakusan Koso
. 2010 Nov;
54(4 Suppl):543-6.
PMID: 21089506
No abstract available.
7.
Endo H, Kawashima S, Sato L, Lai M, Enomoto T, Seki M, et al.
Genes Cells
. 2010 Aug;
15(9):945-58.
PMID: 20718939
Eukaryotic chromatin is regulated by chromatin factors such as histone modification enzymes, chromatin remodeling complexes and histone chaperones in a variety of DNA-dependent reactions. Among these reactions, transcription in the...
8.
Lai M, Seki M, Ui A, Enomoto T
EMBO Rep
. 2007 Jun;
8(7):685-90.
PMID: 17571075
The Saccharomyces cerevisiae RecQ-mediated genome instability (Rmi1) protein was recently identified as the third member of the slow growth suppressor 1-DNA topoisomerase III (Sgs1-Top3) complex, which is required for maintaining...
9.
Ui A, Seki M, Ogiwara H, Lai M, Yamamoto K, Tada S, et al.
Biochem Biophys Res Commun
. 2007 Apr;
356(4):1031-7.
PMID: 17399687
Unequal sister chromatid recombination (uSCR) is elevated in budding yeast sgs1 mutants, which lack a homolog of the human BLM gene that causes Bloom syndrome. Examination of the mechanism responsible...
10.
Ogiwara H, Ui A, Lai M, Enomoto T, Seki M
Biochem Biophys Res Commun
. 2007 Jan;
354(1):222-6.
PMID: 17222391
Deletion mutants of CHL1 or CTF4, which are required for sister chromatid cohesion, showed higher sensitivity to the DNA damaging agents methyl methanesulfonate (MMS), hydroxyurea (HU), phleomycin, and camptothecin, similar...