Molly C Sutherland
Overview
Explore the profile of Molly C Sutherland including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
17
Citations
284
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Yeasmin T, Carroll S, Hawtof D, Sutherland M
Commun Biol
. 2024 Aug;
7(1):984.
PMID: 39138305
Heme trafficking is essential for cellular function, yet mechanisms of transport and/or heme interaction are not well defined. The System I and System II bacterial cytochrome c biogenesis pathways are...
2.
Kreiman A, Yeasmin T, Sutherland M
Methods Mol Biol
. 2024 Jul;
2839:195-211.
PMID: 39008254
Recombinant expression and biogenesis of cytochrome c species is a simple and efficient method for the production of holocytochrome c species, thus presenting an avenue for the study of cytochrome...
3.
Grunow A, Carroll S, Kreiman A, Sutherland M
mBio
. 2023 Nov;
14(6):e0150923.
PMID: 37929956
Heme is an essential co-factor for proteins involved with critical cellular functions, such as energy production and oxygen transport. Thus, understanding how heme interacts with proteins and is moved through...
4.
Mendez D, Lowder E, Tillman D, Sutherland M, Collier A, Rau M, et al.
Nat Chem Biol
. 2021 Dec;
18(1):101-108.
PMID: 34931065
Although the individual structures and respiratory functions of cytochromes are well studied, the structural basis for their assembly, including transport of heme for attachment, are unknown. We describe cryo-electron microscopy...
5.
Keffer J, McAllister S, Garber A, Hallahan B, Sutherland M, Rozovsky S, et al.
mBio
. 2021 Jul;
12(4):e0107421.
PMID: 34311573
Iron (Fe) oxidation is one of Earth's major biogeochemical processes, key to weathering, soil formation, water quality, and corrosion. However, our understanding of microbial contribution is limited by incomplete knowledge...
6.
In vitro reconstitution reveals major differences between human and bacterial cytochrome c synthases
Sutherland M, Mendez D, Babbitt S, Tillman D, Melnikov O, Tran N, et al.
Elife
. 2021 May;
10.
PMID: 33973521
Cytochromes c are ubiquitous heme proteins in mitochondria and bacteria, all possessing a CXXCH (CysXxxXxxCysHis) motif with covalently attached heme. We describe the first in vitro reconstitution of cytochrome c...
7.
Gupta D, Sutherland M, Rengasamy K, Meacham J, Kranz R, Bose A
mBio
. 2019 Nov;
10(6).
PMID: 31690680
Photoferrotrophy is a form of anoxygenic photosynthesis whereby bacteria utilize soluble or insoluble forms of ferrous iron as an electron donor to fix carbon dioxide using light energy. They can...
8.
Sutherland M, Tran N, Tillman D, Jarodsky J, Yuan J, Kranz R
mBio
. 2018 Dec;
9(6).
PMID: 30563894
Although intracellular heme trafficking must occur for heme protein assembly, only a few heme transporters have been unequivocally discovered and nothing is known about their structure or mechanisms. Cytochrome biogenesis...
9.
Sutherland M, Jarodsky J, Ovchinnikov S, Baker D, Kranz R
J Mol Biol
. 2018 Mar;
430(8):1065-1080.
PMID: 29518410
Although many putative heme transporters have been discovered, it has been challenging to prove that these proteins are directly involved with heme trafficking in vivo and to identify their heme...
10.
Sutherland M, Rankin J, Kranz R
Biochemistry
. 2016 May;
55(22):3150-6.
PMID: 27198710
Cytochromes c require covalent attachment of heme via two thioether bonds at conserved CXXCH motifs, a process accomplished in prokaryotes by eight integral membrane proteins (CcmABCDEFGH), termed System I. Heme...