Mohsen Javam
Overview
Explore the profile of Mohsen Javam including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
150
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0
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Recent Articles
1.
Imperio G, Javam M, Lye P, Constantinof A, Dunk C, Reis F, et al.
J Cell Mol Med
. 2018 Nov;
23(1):610-618.
PMID: 30407748
The ATP-binding cassette (ABC) transporters control placental transfer of several nutrients, steroids, immunological factors, chemicals, and drugs at the maternal-fetal interface. We and others have demonstrated a gestational age-dependent expression...
2.
Dunk C, Pappas J, Lye P, Kibschull M, Javam M, Bloise E, et al.
J Cell Mol Med
. 2018 Sep;
22(11):5378-5393.
PMID: 30256530
Dysregulation of trophoblast differentiation is implicated in the placental pathologies of intrauterine growth restriction and pre-eclampsia. P-glycoprotein (P-gp encoded by ABCB1) is an ATP-binding cassette transporter present in the syncytiotrophoblast...
3.
Eustaquio Do Imperio G, Bloise E, Javam M, Lye P, Constantinof A, Dunk C, et al.
Cell Physiol Biochem
. 2018 Feb;
45(2):591-604.
PMID: 29402780
Background/aims: The ATP-binding cassette (ABC) transporters mediate drug biodisposition and immunological responses in the placental barrier. In vitro infective challenges alter expression of specific placental ABC transporters. We hypothesized that...
4.
Lye P, Bloise E, Javam M, Gibb W, Lye S, Matthews S
Am J Pathol
. 2015 May;
185(6):1666-75.
PMID: 25963552
The ABC transporters P-glycoprotein (P-gp, official gene symbol ABCB1) and breast cancer resistance protein (BCRP, official gene symbol ABCG2) protect the conceptus from exposure to toxins and xenobiotics present in...
5.
Baello S, Iqbal M, Bloise E, Javam M, Gibb W, Matthews S
Endocrinology
. 2013 Nov;
155(2):475-84.
PMID: 24265456
P-glycoprotein (P-gp), an efflux transporter encoded by the abcb1 gene, protects the developing fetal brain. Levels of P-gp in endothelial cells of the blood-brain barrier (BBB) increase dramatically during the...
6.
Bloise E, Bhuiyan M, Audette M, Petropoulos S, Javam M, Gibb W, et al.
PLoS One
. 2013 Jun;
8(6):e65728.
PMID: 23762418
Lipopolysaccharide (LPS) in high doses inhibits placental multidrug resistance P-glycoprotein (P-gp--Abcb1a/b) and breast cancer resistance protein (BCRP--Abcg2). This potentially impairs fetal protection against harmful factors in the maternal circulation. However,...