Mohansrinivas Chennakesavalu
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Explore the profile of Mohansrinivas Chennakesavalu including associated specialties, affiliations and a list of published articles.
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11
Citations
250
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Recent Articles
1.
Pomaville M, Chennakesavalu M, Wang P, Jiang Z, Sun H, Ren P, et al.
Cell Rep
. 2024 May;
43(5):114165.
PMID: 38691450
The N-methyladenosine (mA) RNA modification is an important regulator of gene expression. mA is deposited by a methyltransferase complex that includes methyltransferase-like 3 (METTL3) and methyltransferase-like 14 (METTL14). High levels...
2.
Chennakesavalu M, Moore K, Chaves G, Veeravalli S, Terhaar R, Wu T, et al.
JCO Precis Oncol
. 2024 Jan;
8:e2300297.
PMID: 38295320
Purpose: Neuroblastoma is the most common extracranial solid tumor in childhood. We previously showed that circulating cell-free DNA (cfDNA) and tumor biopsy derived 5-hydroxymethylcytosime (5-hmC) profiles identified patients with neuroblastoma...
3.
Chennakesavalu M, Pudela C, Applebaum M, Lee S, Che Y, Naranjo A, et al.
EJC Paediatr Oncol
. 2024 Jan;
2.
PMID: 38213818
Background: Racial/ethnic survival disparities in neuroblastoma were first reported more than a decade ago. We sought to investigate if these disparities have persisted with current era therapy. Methods: Two patient...
4.
Vayani O, Kaufman M, Moore K, Chennakesavalu M, Terhaar R, Chaves G, et al.
Pediatr Blood Cancer
. 2023 Oct;
71(1):e30735.
PMID: 37859597
Background: Cell-free DNA (cfDNA) profiles of 5-hydroxymethylcytosine (5-hmC), an epigenetic marker of open chromatin and active gene expression, are correlated with metastatic disease burden in patients with neuroblastoma. Neuroblastoma tumors...
5.
Vayani O, Kaufman M, Moore K, Chennakesavalu M, Terhaar R, Chaves G, et al.
bioRxiv
. 2023 Sep;
PMID: 37693610
Background: Cell free DNA (cfDNA) profiles of 5-hydroxymethylcytosine (5-hmC), an epigenetic marker of open chromatin and active gene expression, are correlated with metastatic disease burden in patients with neuroblastoma. Neuroblastoma...
6.
Chennakesavalu M, Moore K, Chaves G, Veeravalli S, Terhaar R, Wu T, et al.
bioRxiv
. 2023 May;
PMID: 37163024
Neuroblastoma is the most common extra-cranial solid tumor in childhood and epigenetic dysregulation is a key driver of this embryonal disease. In cell-free DNA from neuroblastoma patients with high-risk disease,...
7.
Chennakesavalu M, Raghurama R Somala S, Dommaraju S, Peesapati M, Guo K, Rosenblatt M, et al.
Surv Ophthalmol
. 2021 Apr;
66(6):960-976.
PMID: 33811911
Dry eye disease (DED) is a common ocular surface condition causing symptoms of significant discomfort, visual disturbance, and pain. With recent advancements, DED has become recognized as a chronic self-perpetuating...
8.
Mathew B, Torres L, Acha L, Tran S, Liu A, Patel R, et al.
Cells
. 2021 Apr;
10(4).
PMID: 33806128
Cell replacement therapy using mesenchymal (MSC) and other stem cells has been evaluated for diabetic retinopathy and glaucoma. This approach has significant limitations, including few cells integrated, aberrant growth, and...
9.
Mathew B, Chennakesavalu M, Sharma M, Torres L, Stelman C, Tran S, et al.
Autophagy
. 2020 May;
17(6):1479-1499.
PMID: 32452260
Retinal ischemia is a major cause of vision loss and a common underlying mechanism associated with diseases, such as diabetic retinopathy and central retinal artery occlusion. We have previously demonstrated...
10.
Baldwin D, Chennakesavalu M, Gangemi A
Surg Obes Relat Dis
. 2019 Nov;
15(12):2123-2130.
PMID: 31711944
Nonalcoholic fatty liver disease (NAFLD) prevalence is rising worldwide, as a direct consequence of the obesity epidemic. Bariatric surgery provides proven NAFLD amelioration, although questions remain regarding whether Roux-en-Y gastric...