Mohammed Almakadi
Overview
Explore the profile of Mohammed Almakadi including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
250
Followers
0
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Recent Articles
1.
Ebraheem M, Alzahrani I, Crowther M, Rochwerg B, Almakadi M
J Thromb Haemost
. 2020 Jun;
18(9):2308-2317.
PMID: 32510840
Background: Guidelines recommend at least 3 months of anticoagulation for venous thromboembolism (VTE). Evidence supporting indefinite anticoagulation exists in certain conditions; however, for many patients, uncertainty regarding when to discontinue...
2.
Boyd A, Aslostovar L, Reid J, Ye W, Tanasijevic B, Porras D, et al.
Cancer Cell
. 2018 Sep;
34(3):483-498.e5.
PMID: 30205048
Despite successful remission induction, recurrence of acute myeloid leukemia (AML) remains a clinical obstacle thought to be caused by the retention of dormant leukemic stem cells (LSCs). Using chemotherapy-treated AML...
3.
Aslostovar L, Boyd A, Almakadi M, Collins T, Leong D, Tirona R, et al.
Blood Adv
. 2018 Aug;
2(15):1935-1945.
PMID: 30093531
We completed a phase 1 dose-escalation trial to evaluate the safety of a dopamine receptor D2 (DRD2) antagonist thioridazine (TDZ), in combination with cytarabine. Thirteen patients 55 years and older...
4.
Almakadi M, Sheasgreen C, Barefah A, Lu L, Tyagi N, Mazzetti G, et al.
Am J Hematol
. 2017 Nov;
93(2):E42-E45.
PMID: 29119605
No abstract available.
5.
Boyd A, Reid J, Salci K, Aslostovar L, Benoit Y, Shapovalova Z, et al.
Nat Cell Biol
. 2017 Oct;
19(11):1336-1347.
PMID: 29035359
Acute myeloid leukaemia (AML) is distinguished by the generation of dysfunctional leukaemic blasts, and patients characteristically suffer from fatal infections and anaemia due to insufficient normal myelo-erythropoiesis. Direct physical crowding...
6.
Guezguez B, Almakadi M, Benoit Y, Shapovalova Z, Rahmig S, Fiebig-Comyn A, et al.
Cancer Cell
. 2016 Jan;
29(1):61-74.
PMID: 26766591
Initial pathway alternations required for pathogenesis of human acute myeloid leukemia (AML) are poorly understood. Here we reveal that removal of glycogen synthase kinase-3α (GSK-3α) and GSK-3β dependency leads to...