Mohammadparsa Khakpour
Overview
Explore the profile of Mohammadparsa Khakpour including associated specialties, affiliations and a list of published articles.
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9
Citations
16
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Recent Articles
1.
Bobotis B, Khakpour M, Braniff O, de Andrade E, Gargus M, Allen M, et al.
J Neuroinflammation
. 2025 Jan;
22(1):18.
PMID: 39856696
The brain presents various structural and functional sex differences, for which multiple factors are attributed: genetic, epigenetic, metabolic, and hormonal. While biological sex is determined by both sex chromosomes and...
2.
Flury A, Aljayousi L, Park H, Khakpour M, Mechler J, Aziz S, et al.
Neuron
. 2024 Dec;
113(4):554-571.e14.
PMID: 39719704
The brain's primary immune cells, microglia, are a leading causal cell type in Alzheimer's disease (AD). Yet, the mechanisms by which microglia can drive neurodegeneration remain unresolved. Here, we discover...
3.
Jacquet R, Gonzalez Ibanez F, Picard K, Funes L, Khakpour M, Gouras G, et al.
Cell Rep
. 2024 Dec;
43(12):115052.
PMID: 39644493
How microglia digest Alzheimer's fibrillar amyloid-beta (Aβ) plaques that are too large to be phagocytosed is not well understood. Here, we show that primary microglial cells create acidic extracellular compartments,...
4.
De Felice E, Bobotis B, Rigillo G, Khakpour M, de Andrade E, Benatti C, et al.
Brain Behav Immun
. 2024 Dec;
124():192-204.
PMID: 39617070
The hippocampus is a heterogenous structure that exhibits functional segregation along its longitudinal axis. We recently showed that in male mice, microglia, the brain's resident immune cells, differ between the...
5.
Vecchiarelli H, Bisht K, Sharma K, Novak S, Traetta M, Garcia-Segura M, et al.
bioRxiv
. 2024 Oct;
PMID: 39463930
This study examined dark microglia-a state linked to central nervous system pathology and neurodegeneration-during postnatal development in the mouse ventral hippocampus, finding that dark microglia interact with blood vessels and...
6.
Ghorbani S, Li C, Lozinski B, Moezzi D, DMello C, Dong Y, et al.
J Clin Invest
. 2024 May;
134(13).
PMID: 38743490
Impairment of oligodendrocytes and myelin contributes to neurological disorders including multiple sclerosis (MS), stroke, and Alzheimer's disease. Regeneration of myelin (remyelination) decreases the vulnerability of demyelinated axons, but this repair...
7.
Ben-Azu B, Del Re E, VanderZwaag J, Carrier M, Keshavan M, Khakpour M, et al.
Front Cell Neurosci
. 2023 May;
17:1139357.
PMID: 37256150
Brain aging, which involves a progressive loss of neuronal functions, has been reported to be premature in probands affected by schizophrenia (SCZ). Evidence shows that SCZ and accelerated aging are...
8.
St-Pierre M, Carrier M, Gonzalez Ibanez F, Khakpour M, Wallman M, Parent M, et al.
J Neuroinflammation
. 2023 Mar;
20(1):73.
PMID: 36918925
The past decade has witnessed increasing evidence for a crucial role played by glial cells, notably astrocytes, in Alzheimer's disease (AD). To provide novel insights into the roles of astrocytes...
9.
Khakpour M, Gonzalez Ibanez F, Bordeleau M, Picard K, Mckee-Reid L, Ben-Azu B, et al.
Micron
. 2022 Aug;
161:103334.
PMID: 35970079
Microglia, the immune resident cells of the central nervous system (CNS), are now recognized as performing crucial roles for maintaining homeostasis and determining the outcomes of various pathological challenges across...
10.
Ezzati K, Ravarian B, Saberi A, Salari A, Reyhanian Z, Khakpour M, et al.
Arch Bone Jt Surg
. 2021 May;
9(2):230-234.
PMID: 34026942
Background: Nonspecific chronic neck pain is increasing according to work-related gestures and modern lifestyle. Myofascial pain syndrome is a common problem and may be a primary disease. This study was...