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Mohammad Qneibi

Explore the profile of Mohammad Qneibi including associated specialties, affiliations and a list of published articles. Areas
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Articles 28
Citations 177
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Recent Articles
1.
Natsheh H, Qneibi M, Kittana N, Jaradat N, Assali M, Shaqour B, et al.
Int J Pharm . 2024 Dec; 670:125111. PMID: 39710306
Aim: This study focuses on the design and investigation a transethosomal formulation for enhanced topical delivery and improved analgesic activity of caryophyllene oxide. In addition, this work explores new potential...
2.
Qneibi M, Bdir S, Bdair M, Aldwaik S, Heeh M, Sandouka D, et al.
FEBS J . 2024 Oct; PMID: 39394632
α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) ionotropic glutamate receptors (AMPARs) mediate rapid excitatory synaptic transmission in the mammalian brain, primarily driven by the neurotransmitter glutamate. The modulation of AMPAR activity, particularly calcium-permeable AMPARs...
3.
Hawash M, Jaradat N, Abualhasan M, Jadallah J, Fashafsheh L, Zaid S, et al.
3 Biotech . 2024 Oct; 14(10):255. PMID: 39350934
We investigated the hypoglycemic activity and pharmacokinetic study of two synthesized benzoyl benzodioxol derivatives, compound I (methyl 2-(6-(2-bromobenzoyl)benzo[][1,3]dioxol-5-yl)acetate), and compound II, 2-(6-benzoylbenzo[][1,3]dioxol-5-yl)acetic acid, which showed very strong α-amylase inhibiting activity...
4.
Qneibi M, Hawash M, Bdir S, Bdair M, Aldwaik S
Molecules . 2024 Jul; 29(13). PMID: 38999182
An optimal balance between excitatory and inhibitory transmission in the central nervous system provides essential neurotransmission for good functioning of the neurons. In the neurology field, a disturbed balance can...
5.
Hawash M, Qneibi M, Natsheh H, Mohammed N, Hamda L, Kumar A, et al.
ACS Chem Neurosci . 2024 May; 15(11):2334-2349. PMID: 38747411
Parkinson's disease (PD) is a significant health issue because it gradually damages the nervous system. α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors play a significant role in the development of PD. The current...
6.
Qneibi M, Bdir S, Bdair M, Aldwaik S, Sandouka D, Heeh M, et al.
Eur J Med Chem . 2024 Jan; 266:116151. PMID: 38237342
The neuropharmacological community has shown a strong interest in AMPA receptors as critical components of excitatory synaptic transmission during the last fifteen years. AMPA receptors, members of the ionotropic glutamate...
7.
Rahhal B, Qneibi M, Jaradat N, Hawash M, Qadi M, Issa L, et al.
BMC Complement Med Ther . 2024 Jan; 24(1):27. PMID: 38195607
Background: Plants have historically been a rich source of medicinal compounds, with many modern pharmaceuticals derived from botanical origins. In contemporary healthcare, there is a resurgence in utilizing botanical substances...
8.
Qneibi M, Hawash M, Gumus M, Capan I, Sert Y, Bdir S, et al.
Mol Neurobiol . 2023 Dec; 61(7):4565-4576. PMID: 38105408
In the 1980s, the identification of specific pharmacological antagonists played a crucial role in enhancing our comprehension of the physiological mechanisms associated with α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors (AMPARs). The...
9.
Hawash M, Al-Smadi D, Kumar A, Olech B, Dominiak P, Jaradat N, et al.
Biomolecules . 2023 Oct; 13(10). PMID: 37892167
In this study, we synthesized benzodioxol carboxamide derivatives and investigated their antidiabetic potential. The synthesized compounds ( and ) underwent characterization via HRMS, H-, CAPT-NMR, and MicroED. Their efficacy against...
10.
Qneibi M, Bdir S, Maayeh C, Bdair M, Sandouka D, Basit D, et al.
Neurochem Res . 2023 Sep; 49(2):258-289. PMID: 37768469
Numerous studies have demonstrated essential oils' diverse chemical compositions and pharmacological properties encompassing antinociceptive, anxiolytic-like, and anticonvulsant activities, among other notable effects. The utilization of essential oils, whether inhaled, orally...