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Mohammad HamediRad

Explore the profile of Mohammad HamediRad including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 375
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Recent Articles
1.
Shamsi M, Mirzaei M, HamediRad M
BMC Sports Sci Med Rehabil . 2020 Apr; 12:24. PMID: 32313659
Background: Low back pain causes changes in muscle activation patterns. Knowing how different exercises may improve altered muscle activation is useful in the treatment of patients. The aim of the...
2.
Lian J, Schultz C, Cao M, HamediRad M, Zhao H
Nat Commun . 2019 Dec; 10(1):5794. PMID: 31857575
Genome-scale engineering is an indispensable tool to understand genome functions due to our limited knowledge of cellular networks. Unfortunately, most existing methods for genome-wide genotype-phenotype mapping are limited to a...
3.
HamediRad M, Chao R, Weisberg S, Lian J, Sinha S, Zhao H
Nat Commun . 2019 Nov; 10(1):5150. PMID: 31723141
Large-scale data acquisition and analysis are often required in the successful implementation of the design, build, test, and learn (DBTL) cycle in biosystems design. However, it has long been hindered...
4.
HamediRad M, Weisberg S, Chao R, Lian J, Zhao H
ACS Synth Biol . 2019 Apr; 8(5):1047-1054. PMID: 31013062
Golden Gate assembly is one of the most widely used DNA assembly methods due to its robustness and modularity. However, despite its popularity, the need for BsaI-free parts, the introduction...
5.
Tasan I, Sustackova G, Zhang L, Kim J, Sivaguru M, HamediRad M, et al.
Nucleic Acids Res . 2018 Jun; 46(17):e100. PMID: 29912475
Nuclear organization has an important role in determining genome function; however, it is not clear how spatiotemporal organization of the genome relates to functionality. To elucidate this relationship, a method...
6.
Bao Z, HamediRad M, Xue P, Xiao H, Tasan I, Chao R, et al.
Nat Biotechnol . 2018 May; 36(6):505-508. PMID: 29734295
We developed a CRISPR-Cas9- and homology-directed-repair-assisted genome-scale engineering method named CHAnGE that can rapidly output tens of thousands of specific genetic variants in yeast. More than 98% of target sequences...
7.
HamediRad M, Lian J, Li H, Zhao H
Biotechnol Bioeng . 2018 Feb; 115(6):1552-1560. PMID: 29460286
Xylose is a major component of lignocellulosic biomass, one of the most abundant feedstocks for biofuel production. Therefore, efficient and rapid conversion of xylose to ethanol is crucial in the...
8.
Lian J, HamediRad M, Zhao H
Biotechnol J . 2018 Feb; 13(9):e1700601. PMID: 29436783
Thanks to its ease of use, modularity, and scalability, the clustered regularly interspaced short palindromic repeats (CRISPR) system has been increasingly used in the design and engineering of Saccharomyces cerevisiae,...
9.
Lian J, HamediRad M, Hu S, Zhao H
Nat Commun . 2017 Nov; 8(1):1688. PMID: 29167442
Designing an optimal microbial cell factory often requires overexpression, knock-down, and knock-out of multiple gene targets. Unfortunately, such rewiring of cellular metabolism is often carried out sequentially and with low...
10.
Garcia-Ruiz E, HamediRad M, Zhao H
Adv Biochem Eng Biotechnol . 2016 Sep; 162:77-116. PMID: 27629378
The microbial metabolic versatility found in nature has inspired scientists to create microorganisms capable of producing value-added compounds. Many endeavors have been made to transfer and/or combine pathways, existing or...