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» Authors » Mohamed A Mahmoud

Mohamed A Mahmoud

Explore the profile of Mohamed A Mahmoud including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 52
Citations 210
Followers 0
Related Specialties
Anesthesiology
General Medicine
Biochemistry
Top 10 Co-Authors
Bahaa G M Youssif
Saleh A Bakheet
Ahmed Nadeem
Mushtaq A Ansari
Sabry M Attia
Sheikh F Ahmad
Mayasar I Al-Zaban
Mahmoud Alagawany
Stefan Brase
Ayman S Salah
Published In
Biol Trace Elem Res
Mutat Res Genet Toxicol Environ Mutagen
Paediatr Anaesth
Can J Anaesth
Saudi J Biol Sci
Affiliations
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Recent Articles
1.
Heterogeneity of the Immunological and Pathogenic Profiles in Patients Hospitalize Early Versus Late During an Acute Vital Illness as Shown in Native SARS-CoV-2 Infection
Laudanski K, Sayed Ahmed A, Mahmoud M, Antar M, Gad H
Int J Mol Sci . 2025 Mar; 26(5). PMID: 40076968
The immune system's response to an invading pathogen is the critical determinant in recovery from illness. Here, we hypothesize that the immune response will swiftly follow classical activation and a...
2.
The PPAR-α selective agonist WY14643 improves lupus nephritis via the downregulation of the RORγT/STAT3 signaling pathway in MRL/lpr mice
Al-Mazroua H, Nadeem A, Attia S, Bakheet S, Ahmad A, Ansari M, et al.
Int Immunopharmacol . 2024 Dec; 145:113787. PMID: 39653614
Systemic lupus erythematosus (SLE) is a classic autoimmune disorder that mostly affects young women and involves various organs, such as the skin, joints, central nervous system, and kidneys. WY14643, a...
3.
The ameliorative effect of pioglitazone against colistin-induced nephrotoxicity is mediated by inhibition of NF-κB and restoration of Nrf2 signaling: An integrative bioinformatics prediction-guided in vitro study
Alharbi M, Mahmoud M, Alshammari A, Almutairi M, Al-Ghamdi J, Alsabhan J, et al.
PLoS One . 2024 Dec; 19(12):e0314092. PMID: 39621679
Pioglitazone, an anti-diabetic drug, has been previously shown to ameliorate kidney damage through anti-inflammatory and antioxidant effects. In this study, we employed an integrative bioinformatics approach to study the possible...
4.
Synthesis and Antimicrobial Evaluation of New 1,2,4-Triazolo[1,5-]pyrimidine-Based Derivatives as Dual Inhibitors of Bacterial DNA Gyrase and DHFR
Al-Wahaibi L, Rabea S, Mahmoud M, Youssif B, Brase S, Abdel-Aziz S
ACS Omega . 2024 Dec; 9(47):47261-47273. PMID: 39619536
A series of 1,2,4-triazolo[1,5-]pyrimidine-based derivatives were developed and prepared by reacting chalcones - with 3-phenyl-1,2,4-triazole-5-amine (). The novel compounds were analyzed using several spectroscopic techniques, and their antimicrobial efficacies against...
5.
Synthesis, enzyme inhibition, and docking studies of new schiff bases of disalicylic acid methylene-based derivatives as dual-target antibacterial agents
Al-Wahaibi L, Mahmoud M, Alzahrani H, Abou-Zied H, Abdelmoez A, Youssif B, et al.
Front Chem . 2024 Nov; 12:1493906. PMID: 39600312
Introduction: Bacteria have acquired resistance to almost all antibiotics currently in use due to their extensive, broad, and improper utilization over a prolonged period. DNA gyrase and DHFR exhibit significant...
6.
Salubrious effects of proanthocyanidins on behavioral phenotypes and DNA repair deficiency in the BTBR mouse model of autism
Alhusain A, Mahmoud M, Alhamami H, Ebrahim Alobid S, Ansari M, Ahmad S, et al.
Saudi Pharm J . 2024 Nov; 32(11):102187. PMID: 39493830
Autism is a neurodevelopmental disorder distinguished by impaired social interaction and repetitive behaviors. Global estimates indicate that autism affects approximately 1.6% of children, with the condition progressively becoming more prevalent...
7.
Assessing Residual Gastric Fluid Volume after Administering Diluted Oral Contrast until One Hour Prior to Anesthesia in Children: An Observational Cohort Study
Narayanasamy S, Fleck R, Kandil A, Afonya B, Mahmoud H, Lee J, et al.
J Clin Med . 2024 Jun; 13(12). PMID: 38930113
Gastric fluid volume has been used as a surrogate marker for pulmonary aspiration risk in studies evaluating fasting protocol safety. This study measured residual gastric fluid volume in children using...
8.
Discovery of new Schiff bases of the disalicylic acid scaffold as DNA gyrase and topoisomerase IV inhibitors endowed with antibacterial properties
Al-Wahaibi L, Mahmoud M, Alzahrani H, Abou-Zied H, Gomaa H, Youssif B, et al.
Front Chem . 2024 Jun; 12:1419242. PMID: 38911996
DNA gyrase and topoisomerase IV show great potential as targets for antibacterial medicines. In recent decades, various categories of small molecule inhibitors have been identified; however, none have been effective...
9.
Ultrasound-Facilitated, Catheter-Directed Thrombolysis for Acute Pulmonary Embolism
Elheet A, Elhadidy A, Farrag M, Mahmoud M, Ibrahim A, AlAbdali A, et al.
Cureus . 2024 May; 16(3):e57345. PMID: 38690498
Background: Acute pulmonary embolism (APE) poses a significant risk to patient health, with treatment options varying in efficacy and safety. Ultrasound-facilitated catheter-directed thrombolysis (USCDT) has emerged as a potential alternative...
10.
Immunological Signatures in Blood and Urine in 80 Individuals Hospitalized during the Initial Phase of COVID-19 Pandemic with Quantified Nicotine Exposure
Laudanski K, Mahmoud M, Sayed Ahmed A, Susztak K, Mathew A, Chen J
Int J Mol Sci . 2024 Apr; 25(7). PMID: 38612525
This research analyzes immunological response patterns to SARS-CoV-2 infection in blood and urine in individuals with serum cotinine-confirmed exposure to nicotine. Samples of blood and urine were obtained from a...