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Mlana Lore

Explore the profile of Mlana Lore including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Kolakada D, Campbell A, Galvis L, Li Z, Lore M, Jagannathan S
Nucleic Acids Res . 2024 Feb; 52(6):e34. PMID: 38375914
Nonsense-mediated mRNA decay (NMD) is a network of pathways that degrades transcripts that undergo premature translation termination. In mammals, NMD can be divided into the exon junction complex (EJC)-enhanced and...
2.
Kolakada D, Fu R, Biziaev N, Shuvalov A, Lore M, Campbell A, et al.
bioRxiv . 2024 Jan; PMID: 38260612
Nonsense variants underlie many genetic diseases. The phenotypic impact of nonsense variants is determined by nonsense-mediated mRNA decay (NMD), which degrades transcripts with premature termination codons (PTCs). Despite its clinical...
3.
Kolakada D, Campbell A, Galvis L, Li Z, Lore M, Jagannathan S
bioRxiv . 2023 Nov; PMID: 38014198
Nonsense-mediated mRNA decay (NMD) is a network of pathways that degrades transcripts that undergo premature translation termination. In mammals, NMD can be divided into the exon junction complex (EJC)-enhanced and...
4.
Munoz O, Lore M, Jagannathan S
Biochem Soc Trans . 2023 May; 51(3):1121-1129. PMID: 37145092
Nonsense-mediated RNA decay (NMD) plays a dual role as an RNA surveillance mechanism against aberrant transcripts containing premature termination codons and as a gene regulatory mechanism for normal physiological transcripts....