Mitsutoshi Tsukimoto
Overview
Explore the profile of Mitsutoshi Tsukimoto including associated specialties, affiliations and a list of published articles.
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84
Citations
1334
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Recent Articles
1.
Takenaka Y, Tanaka T, Otaki S, Kanbe A, Morita T, Yokoi K, et al.
Biol Pharm Bull
. 2024 Dec;
47(12):2101-2118.
PMID: 39710379
Excessive inflammatory responses to viral infections, known as cytokine storms, are caused by overactivation of endolysosomal Toll-like receptors (TLRs) (TLR3, TLR7, TLR8, and TLR9) and can be lethal, but no...
2.
Ohshima Y, Tsukimoto M, Watanabe S, Tsushima Y, Ishioka N
Biol Pharm Bull
. 2024 Nov;
47(11):1868-1875.
PMID: 39537170
Intracellular ATP is released outside cells by various stimuli and is involved in cytoprotection by activating purinergic receptors. However, it remains unclear whether targeted radionuclide therapy induces extracellular ATP release....
3.
Mizoguchi Y, Kamimura M, Kitabatake K, Uchiumi F, Aoki S, Tsukimoto M
Biochem Biophys Rep
. 2024 Aug;
39:101792.
PMID: 39149414
In recent years, it has become clear that the cytotoxicity of γ-irradiation of cells is increased under microgravity conditions. However, there has been no study of the effect of the...
4.
Seki H, Kitabatake K, Tanuma S, Tsukimoto M
Biochim Biophys Acta Gen Subj
. 2024 Jun;
1868(9):130650.
PMID: 38830560
Glioblastoma (GBM), a highly aggressive malignant tumor of the central nervous system, is mainly treated with radiotherapy. However, since irradiation may lead to the acquisition of migration ability by cancer...
5.
Takenaka Y, Tanaka R, Kitabatake K, Uchiumi F, Aoki S, Kuramochi K, et al.
Biol Pharm Bull
. 2024 May;
47(5):946-954.
PMID: 38735732
There is accumulating evidence that selective serotonin reuptake inhibitors (SSRIs), clinically used as antidepressants, have a beneficial effect on inflammatory diseases such as coronavirus disease 2019 (COVID-19). We previously compared...
6.
Fujie T, Kobayashi M, Ikeuchi L, Nakano T, Kitabatake K, Shinoda Y, et al.
J Toxicol Sci
. 2024 Mar;
49(4):193-208.
PMID: 38556355
Vascular endothelial cells serve as barriers between blood components and subendothelial tissue and regulate the blood coagulation-fibrinolytic system. Ionizing radiation is a common physical stimulant that induces a bystander effect...
7.
Ozaki A, Matsuda A, Maemura Y, Tada Y, Kasai T, Nagashima Y, et al.
Anticancer Res
. 2023 Dec;
44(1):37-47.
PMID: 38160009
Background/aim: We have reported that p62 (also known as sequestosome 1) is needed for survival/proliferation and tumor formation by aldehyde dehydrogenase 1 (ALDH1) -positive cancer stem cells (CSCs) and that...
8.
Oyama M, Sakamoto M, Kitabatake K, Shiina K, Kitahara D, Onozawa S, et al.
Biol Pharm Bull
. 2023 Nov;
47(1):60-71.
PMID: 37926527
Residual cancer cells after radiation therapy may acquire malignant phenotypes such as enhanced motility and migration ability, and therefore it is important to identify targets for preventing radiation-induced malignancy in...
9.
Hotani A, Kitabatake K, Tsukimoto M
Biol Pharm Bull
. 2023 Oct;
47(1):14-22.
PMID: 37880111
Though the physiological effects of adenosine and adenine nucleotides on purinergic receptors in cancer cells have been well studied, the influence of extracellular guanosine and guanine nucleotides on breast cancer...
10.
Takenaka Y, Tanaka R, Kitabatake K, Kuramochi K, Aoki S, Tsukimoto M
Front Pharmacol
. 2022 Jul;
13:874375.
PMID: 35814203
Excessive proinflammatory cytokine production induced by abnormal activation of Toll-like receptor (TLR) signaling, for example, by SARS-CoV-2 infection, can cause a fatal cytokine storm. The selective serotonin reuptake inhibitors (SSRIs)...