Mitsuru Notoya
Overview
Explore the profile of Mitsuru Notoya including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
111
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0
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Recent Articles
1.
Yoshimura N, Yamada K, Ono T, Notoya M, Yukioka H, Takahashi R, et al.
Clin Exp Nephrol
. 2023 Jul;
27(11):901-911.
PMID: 37490135
Background: Uremic toxins accumulate in renal tissues and cells due to chronic kidney disease (CKD). Abnormalities in nicotinamide adenine dinucleotide (NAD +) metabolism lead to the progression of CKD. NAD ...
2.
Takagi H, Tanimoto K, Shimazaki A, Tonomura Y, Momosaki S, Sakamoto S, et al.
J Pharmacol Exp Ther
. 2020 Jan;
372(3):256-263.
PMID: 31900320
Excess intramyocellular lipid (IMCL) deposition in skeletal muscle is closely associated with insulin resistance. Pharmacological inhibition of acetyl-CoA carboxylase (ACC) 2 offers a promising approach to treat insulin resistance through...
3.
Kouno T, Akiyama N, Ito T, Fujieda K, Nanchi I, Okuda T, et al.
Endocr J
. 2017 Jun;
64(Suppl.):S21-S23.
PMID: 28652538
The octanoyl modification of ghrelin by ghrelin O-acyltransferase (GOAT) is essential for exerting its physiologic actions. Since exogenous acylated-ghrelin has shown to stimulate food intake in humans and rodents, GOAT...
4.
Kouno T, Akiyama N, Ito T, Okuda T, Nanchi I, Notoya M, et al.
J Endocrinol
. 2015 Dec;
228(2):115-25.
PMID: 26645250
Ghrelin is an appetite-stimulating hormone secreted from stomach. Since the discovery that acylation of the serine-3 residue by ghrelin O-acyltransferase (GOAT) is essential for exerting its functions, GOAT has been...
5.
Kuroda T, Masui M, Notoya M, Ito M, Tamura Y, Okamoto H, et al.
Nephron Extra
. 2012 Jun;
2(1):133-46.
PMID: 22739248
Background/aim: Matrix metalloproteinases (MMPs) play pivotal roles in extracellular matrix turnover and are involved in chronic kidney disease. The renoprotective action of a synthetic MMP inhibitor, compound A, was investigated...
6.
Kobayashi T, Akiyama Y, Akiyama N, Katoh H, Yamamoto S, Funatsuki K, et al.
Eur J Pharmacol
. 2010 Sep;
649(1-3):23-8.
PMID: 20826135
Irbesartan, an angiotensin II type 1 receptor blocker has been reported to alleviate metabolic disorder in animal studies and human clinical trials. Although this effect may be related to the...
7.
Kobayashi T, Notoya M, Shinosaki T, Kurihara H
Nephron Exp Nephrol
. 2009 Aug;
113(3):e89-96.
PMID: 19684413
Background/aims: Morphological change of podocytes is closely correlated with the development of proteinuria. Podocalyxin is a major sialoglycoprotein of the podocytes and is thought to be involved in the maintenance...
8.
Kuroda T, Tanioka H, Masui M, Ito M, Notoya M, Shinosaki T
Nephron Exp Nephrol
. 2006 Oct;
104(4):e169-82.
PMID: 17028444
Background/aim: Matrix production and degradation are critically important in chronic nephritis. Our aim was to investigate the precise expression of matrix-related molecules which is essential for understanding the pathogenesis of...
9.
Horie K, Sakagami M, Masuda K, Notoya M, Hamana H, Yoshikawa T, et al.
Biol Pharm Bull
. 2004 Aug;
27(8):1275-80.
PMID: 15305036
We have previously found that carboxymethylpullulan (CMPul) conjugated with sialyl Lewis X (Neu5Acalpha2-3Galbeta1-4(Fucalpha1-3)GlcNAc-, 2-3SLex) preferentially accumulates in the lymph nodes and spleen. In the present study, we investigated the structural...
10.
Taoka T, Fujioka M, Matsuo Y, Notoya M, Iwasaki S, Fukusumi A, et al.
Magn Reson Imaging
. 2004 Mar;
22(2):221-7.
PMID: 15010114
To examine the correlation between tissue water content and signal intensity on fluid-attenuated inversion recovery (FLAIR) images, we analyzed infarcted rat brain, verified the results by theoretical simulation, and compared...