Mitsukuni Yoshida
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Explore the profile of Mitsukuni Yoshida including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
1103
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Recent Articles
1.
Yoshida M, Park P, Thang L
Pain Med
. 2025 Mar;
PMID: 40036562
Objective: Shoulder pain is a prevalent musculoskeletal disorder, affecting up to 70% of adults over their lifetime. Recently radiofrequency ablation (RFA) has gained attention as a treatment for joint pain....
2.
Terao R, Sohn B, Yamamoto T, Lee T, Colasanti J, Pfeifer C, et al.
Invest Ophthalmol Vis Sci
. 2024 Aug;
65(10):29.
PMID: 39167399
Purpose: Dysregulated cholesterol metabolism is critical in the pathogenesis of AMD. Cellular senescence contributes to the development of numerous age-associated diseases. In this study, we investigated the link between cholesterol...
3.
Terao R, Lee T, Colasanti J, Pfeifer C, Lin J, Santeford A, et al.
Cell Rep
. 2024 Apr;
43(5):114102.
PMID: 38636518
Although dysregulated cholesterol metabolism predisposes aging tissues to inflammation and a plethora of diseases, the underlying molecular mechanism remains poorly defined. Here, we show that metabolic and genotoxic stresses, convergently...
4.
5.
Yoshida M, Satoh A, Lin J, Mills K, Sasaki Y, Rensing N, et al.
Cell Metab
. 2019 Jun;
30(2):329-342.e5.
PMID: 31204283
Aging is a significant risk factor for impaired tissue functions and chronic diseases. Age-associated decline in systemic NAD availability plays a critical role in regulating the aging process across many...
6.
Lin J, Kubota S, Ban N, Yoshida M, Santeford A, Sene A, et al.
Cell Rep
. 2016 Sep;
17(1):69-85.
PMID: 27681422
Photoreceptor death is the endpoint of many blinding diseases. Identifying unifying pathogenic mechanisms in these diseases may offer global approaches for facilitating photoreceptor survival. We found that rod or cone...
7.
Nguyen A, Yoshida M, Goodarzi H, Tavazoie S
Nat Commun
. 2016 May;
7:11246.
PMID: 27138336
Individual cells within a tumour can exhibit distinct genetic and molecular features. The impact of such diversification on metastatic potential is unknown. Here we identify clonal human breast cancer subpopulations...
8.
Fish L, Pencheva N, Goodarzi H, Tran H, Yoshida M, Tavazoie S
Genes Dev
. 2016 Feb;
30(4):386-98.
PMID: 26883358
Post-transcriptional deregulation is a defining feature of metastatic cancer. While many microRNAs have been implicated as regulators of metastatic progression, less is known about the roles and mechanisms of RNA-binding...
9.
SIRT1-Mediated eNAMPT Secretion from Adipose Tissue Regulates Hypothalamic NAD+ and Function in Mice
Yoon M, Yoshida M, Johnson S, Takikawa A, Usui I, Tobe K, et al.
Cell Metab
. 2015 Apr;
21(5):706-17.
PMID: 25921090
Nicotinamide phosphoribosyltransferase (NAMPT), the key NAD(+) biosynthetic enzyme, has two different forms, intra- and extracellular (iNAMPT and eNAMPT), in mammals. However, the significance of eNAMPT secretion remains unclear. Here we...
10.
Stanley S, Gagner J, Damanpour S, Yoshida M, Dordick J, Friedman J
Science
. 2012 May;
336(6081):604-8.
PMID: 22556257
Medical applications of nanotechnology typically focus on drug delivery and biosensors. Here, we combine nanotechnology and bioengineering to demonstrate that nanoparticles can be used to remotely regulate protein production in...