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Mitsuhiro Okamoto

Explore the profile of Mitsuhiro Okamoto including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 67
Citations 1245
Followers 0
Related Specialties
Endocrinology
Cardiology & Vascular Diseases
Biochemistry
Top 10 Co-Authors
Takayuki Masaki
Hirotaka Shibata
Koro Gotoh
Hiroshi Takemori
Yuichi Yoshida
Yoshinori Ozeki
Shotaro Miyamoto
Yoshiko Katoh
Junko Doi
Junji Toyama
Published In
J Biol Chem
Hypertens Res
J Endocr Soc
Endocr J
FEBS J
Affiliations
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Recent Articles
1.
Positive Changes in Body Composition and Profiles of Individuals with Diabetes 3 Years Following Laparoscopic Sleeve Gastrectomy in Japanese Patients with Obesity
Ozeki Y, Masaki T, Miyamoto S, Yoshida Y, Okamoto M, Gotoh K, et al.
Nutrients . 2024 Nov; 16(22). PMID: 39599712
Background And Objectives: We analyzed the changes in obesity, glucose metabolism, and body composition over a 3-year period in Japanese patients with obesity following laparoscopic sleeve gastrectomy (LSG). Methods: Body...
2.
Antihypertensive effects and changes in extracellular water content by mineralocorticoid receptor antagonists in patients with primary aldosteronism
Matsuda N, Yoshida Y, Inobe N, Yoshimura M, Iwamoto M, Nagai S, et al.
Hypertens Res . 2024 Nov; 48(2):553-562. PMID: 39543416
In primary aldosteronism (PA), non-suppressible excessive aldosterone secretion due to dietary salt intake significantly contributes to hypertension and cardiovascular complications. Blocking the overactivation of mineralocorticoid receptors (MRs) with mineralocorticoid receptor...
3.
Susceptibility to recombinant SARS-CoV-2 spike protein entry in the lungs of high-fat diet-induced obese mice
Gotoh K, Satoh F, Uesugi H, Noguchi T, Matsuda N, Sada K, et al.
FASEB J . 2024 May; 38(10):e23656. PMID: 38752523
Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Obesity is a major risk factor for the development of COVID-19. Angiotensin-converting enzyme 2 (ACE2) is...
4.
Effects of esaxerenone on blood pressure, urinary albumin excretion, serum levels of NT-proBNP, and quality of life in patients with primary aldosteronism
Yoshida Y, Fujiwara M, Kinoshita M, Sada K, Miyamoto S, Ozeki Y, et al.
Hypertens Res . 2023 Sep; 47(1):157-167. PMID: 37717115
Primary aldosteronism (PA) is typically managed with mineralocorticoid receptor antagonists (MRAs) barring adrenalectomy. The efficacy of esaxerenone, a nonsteroidal MRA, were explored in patients with PA. Various parameters such as...
5.
Associations of Diabetic Retinopathy Severity With High Ambulatory Blood Pressure and Suppressed Serum Renin Levels
Sada K, Yoshida Y, Shibuta K, Kimoto K, Miyamoto S, Ozeki Y, et al.
J Clin Endocrinol Metab . 2023 Jun; 108(12):e1624-e1632. PMID: 37319371
Context: The relationships between serum renin levels, severity of diabetic retinopathy (DR), and 24-hour blood pressure (BP) have not been previously reported. Objective: To explore causes for DR and the...
6.
Pitfalls in the diagnosis and treatment of a hypertensive patient with unilateral primary aldosteronism and contralateral pheochromocytoma: a case report
Miyamoto S, Yoshida Y, Ozeki Y, Okamoto M, Gotoh K, Masaki T, et al.
BMC Endocr Disord . 2023 Feb; 23(1):44. PMID: 36797699
Background: Primary aldosteronism (PA) is a common cause of secondary hypertension, whereas pheochromocytoma is a rare cause of it. Thus, concomitant PA and pheochromocytoma is a very rare condition. Case...
7.
Importance of dietary salt restriction for patients with primary aldosteronism during treatment with mineralocorticoid receptor antagonists: The potential importance of post-treatment plasma renin levels
Yoshida Y, Fujiki R, Kinoshita M, Sada K, Miyamoto S, Ozeki Y, et al.
Hypertens Res . 2022 Oct; 46(1):100-107. PMID: 36229529
We measured dietary salt intake in 26 patients with primary aldosteronism treated with mineralocorticoid receptor antagonists and evaluated whether plasma renin levels were affected by dietary salt intake pre-treatment and...
8.
The Effectiveness of GLP-1 Receptor Agonist Semaglutide on Body Composition in Elderly Obese Diabetic Patients: A Pilot Study
Ozeki Y, Masaki T, Kamata A, Miyamoto S, Yoshida Y, Okamoto M, et al.
Medicines (Basel) . 2022 Sep; 9(9). PMID: 36135828
Background And Objectives: This study aimed to investigate the changes in obesity severity, glucose metabolism, and body composition in patients with obesity and type 2 diabetes mellitus treated with glucagon-like...
9.
The Relationship Between Edema and Body Functions in Patients With Chronic Kidney Disease: A Preliminary Study
Takase R, Nakata T, Aoki K, Okamoto M, Fukuda A, Fukunaga N, et al.
Cureus . 2022 Aug; 14(7):e27118. PMID: 36000120
Introduction: Chronic kidney disease (CKD) is known to be a risk factor for falls. In addition, numerous factors such as impaired body balance and loss of muscle mass were reported...
10.
Re-Assessment of the Oral Salt Loading Test Using a New Chemiluminescent Enzyme Immunoassay Based on a Two-Step Sandwich Method to Measure 24-Hour Urine Aldosterone Excretion
Ozeki Y, Kinoshita M, Miyamoto S, Yoshida Y, Okamoto M, Gotoh K, et al.
Front Endocrinol (Lausanne) . 2022 Apr; 13:859347. PMID: 35388294
Since April 2021, the plasma aldosterone concentration has been measured by chemiluminescent enzyme immunoassay (CLEIA) in Japan. In the present study, we developed a new CLEIA using a two-step sandwich...