Mitsuhiko Osaki
Overview
Explore the profile of Mitsuhiko Osaki including associated specialties, affiliations and a list of published articles.
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Articles
128
Citations
2466
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Recent Articles
11.
Hiramuki Y, Abe S, Uno N, Kazuki K, Takata S, Miyamoto H, et al.
Sci Rep
. 2023 Mar;
13(1):4360.
PMID: 36928364
Dystrophin maintains membrane integrity as a sarcolemmal protein. Dystrophin mutations lead to Duchenne muscular dystrophy, an X-linked recessive disorder. Since dystrophin is one of the largest genes consisting of 79...
12.
Nagata K, Hayashi K, Kumata K, Satoh Y, Osaki M, Nakayama Y, et al.
Endocr J
. 2023 Mar;
70(6):619-627.
PMID: 36908137
Epstein-Barr virus (EBV) is a human herpes virus that latently infects B lymphocytes. When EBV is reactivated, host B cells differentiate into plasma cells and produce IgM-dominant antibodies as well...
13.
Okuda K, Nakahara K, Ito A, Iijima Y, Nomura R, Kumar A, et al.
Nat Commun
. 2023 Feb;
14(1):621.
PMID: 36739439
DNA methyltransferases (DNMTs) catalyze methylation at the C5 position of cytosine with S-adenosyl-L-methionine. Methylation regulates gene expression, serving a variety of physiological and pathophysiological roles. The chemical mechanisms regulating DNMT...
14.
Ueno S, Kokura K, Kuromi Y, Osaki M, Okada F, Kitamura S, et al.
J Toxicol Pathol
. 2022 Nov;
35(4):333-343.
PMID: 36406172
Organoids derived from renal tissue stem cells (KS cells) isolated from the S3 segment of adult rat nephrons have previously been developed and evaluated. However, data regarding the histopathological evaluation...
15.
Izutsu R, Osaki M, Jehung J, Seong H, Okada F
Pathol Res Pract
. 2022 Jul;
237:154015.
PMID: 35843033
The adhesion of circulating cancer cells to vascular endothelial cells is an initial and critical step in distant metastases. Amphoterin-induced gene and open reading frame 2 (AMIGO2) was found to...
16.
Goto K, Morimoto M, Osaki M, Tanio A, Izutsu R, Fujiwara Y, et al.
BMC Cancer
. 2022 Mar;
22(1):280.
PMID: 35296279
Background: Gastric cancer (GC) is one of the most common malignancies, and the liver is the most common site of hematogenous metastasis of GC. AMIGO2 is a type I transmembrane...
17.
Uno N, Takata S, Komoto S, Miyamoto H, Nakayama Y, Osaki M, et al.
Sci Rep
. 2022 Feb;
12(1):3009.
PMID: 35194085
Human artificial chromosomes (HACs) and mouse artificial chromosomes (MACs) are non-integrating chromosomal gene delivery vectors for molecular biology research. Recently, microcell-mediated chromosome transfer (MMCT) of HACs/MACs has been achieved in...
18.
Goto K, Osaki M, Izutsu R, Tanaka H, Sasaki R, Tanio A, et al.
Diagn Pathol
. 2022 Jan;
17(1):16.
PMID: 35094710
Instruction: The human amphoterin-induced gene and open reading frame (AMIGO) was identified as a novel cell adhesion molecule of type I transmembrane protein. AMIGO2 is one of three members of...
19.
Izutsu R, Osaki M, Nemoto H, Jingu M, Sasaki R, Yoshioka Y, et al.
Sci Rep
. 2022 Jan;
12(1):792.
PMID: 35039535
Adhesion of cancer cells to vascular endothelial cells in target organs is an initial step in cancer metastasis. Our previous studies revealed that amphoterin-induced gene and open reading frame 2...
20.
Hoshino Y, Sugihara T, Ikeda S, Tarumoto R, Matsuki Y, Kanda T, et al.
J Nutr Sci Vitaminol (Tokyo)
. 2022 Jan;
67(6):397-403.
PMID: 34980718
In cholestatic liver diseases, coagulopathy is induced by malabsorption of vitamin K. Supplementation of vitamin K has previously been shown to prevent coagulopathy. In this study, we tested the efficacy...